Results 51 to 60 of about 10,246 (237)
Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity
Background Growing evidence supports the use of low-carbohydrate/high-fat ketogenic diets as an adjunctive cancer therapy. However, it is unclear which genetic, metabolic, or immunological factors contribute to the beneficial effect of ketogenic diets ...
Daniela D. Weber +14 more
doaj +1 more source
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata +9 more
wiley +1 more source
ObjectiveKetogenic diets (KDs) have been used in the management of multiple pediatric and adult epilepsies. CER-0001 (tricaprilin) is an orally administered, liquid, investigational ketogenic drug with preclinical efficacy in an infantile spasms (IS ...
Marc Cantillon +8 more
doaj +1 more source
Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases
Ketogenic diets have been shown to play a role in some metabolic diseases and neurodegenerative diseases as a low-carbohydrate, high-fat diets supplemented with appropriate protein. Ketogenic diets have been proven effective, but the mechanisms of action
Yuqi LI +5 more
doaj +1 more source
Ketogenic diets, which are carbohydrate-restricted high-fat diets, may have therapeutic effects on various diseases, including cancer. However, ketogenic diets are often not standardized and, therefore, results are difficult to interpret.
Mariko Takeuchi +11 more
core +1 more source
ABSTRACT Objective A focus on transdiagnostic targets is one of the key strategies for developing effective, efficient, and scalable treatments for mental health conditions. We conducted an umbrella review of recent meta‐analyses (August 2022 to May 2026) to update our understanding of critical transdiagnostic intervention targets that could inform ...
Yuan Zhou +2 more
wiley +1 more source
Future Directions for the Ketogenic Diet Therapy
Future Directions for the Ketogenic Diet ...
Olivotto S., Previtali R.
core +2 more sources
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Ketogenic Metabolic Therapy for Glioma
Purpose: This study describes a retrospective case series of patients with glioma who received ketogenic metabolic therapy through dietary adherence and intermittent fasting.
DiDomenico, Joseph D +6 more
core +1 more source
Cenobamate use in super‐refractory status epilepticus: A report of three cases
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi +11 more
wiley +1 more source

