Results 111 to 120 of about 24,707 (302)
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, EarlyView.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Clinical Genetics, EarlyView.We found key differences between tuberous sclerosis patients with TSC1 and TSC2 variants. Patients carrying TSC2 variants had more severe and earlier‐onset symptoms. We also identified two distinct clinical subgroups which follow different disease courses: one characterized by predominant renal involvement and the other by more pronounced neurological ...
Hila Weisblum Neuman +6 more
wiley +1 more source
Ketogenic diet in the treatment of epilepsy in children under the age of 2 years: study protocol for a randomised controlled trial [PDF]
, 2017 Siobhan Titre-Johnson +17 more
openalex +1 more source
Developmental Medicine &Child Neurology, EarlyView.Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70075 Abstract Aim To evaluate personalized care or precision medicine initiatives, including mobile health (mHealth) technology and genetic screening, in a South African paediatric epilepsy clinic. Method This exploratory prospective observational pilot study included 39 children
Ian S. Olivier +12 more
wiley +1 more source
Characterizing the fecal microbiome in patients on the ketogenic diet for drug resistant epilepsy
HeliyonBackground: The ketogenic diet is a dietary therapy with anti-seizure effects. The efficacy of the diet is variable, with initial animal studies suggesting the intestinal microbiome may have a modulating effect.
Alexander Freibauer +2 more
doaj +1 more source
Developmental Medicine &Child Neurology, EarlyView.This multicenter retrospective study evaluated the use of intravenous immunoglobulin (IVIG) in 14 children with Dravet syndrome as a preventive strategy against febrile status epilepticus. Over a 6‐month period, IVIG was associated with a significant reduction in hospitalizations for febrile status epilepticus.
Romane Marc +9 more
wiley +1 more source
The effect of the ketogenic diet on resistance training load management: a repeated-measures clinical trial in trained participants [PDF]
Salvador Vargas-Molina +5 more
openalex +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims Obesity and type 2 diabetes mellitus (T2DM) are among the leading global health challenges of the 21st century. While caloric restriction remains the cornerstone of weight loss interventions, ketogenic diets (KD), characterised by low carbohydrate and high fat intake, have been shown to improve metabolic health partly by modulating the ...
June Stone +5 more
wiley +1 more source
Clinical and genetic landscape of epilepsies with absence seizures and single‐gene etiology
Epilepsia, EarlyView.Abstract Objective To characterize the clinical, electroencephalographic, and genetic features of epilepsies featuring absence seizures within monogenic etiology, highlighting the diagnostic, treatment and prognostic implications. Methods We conducted a retrospective, multicenter study including patients with monogenic epilepsies and ...
Simona Balestrini +50 more
wiley +1 more source