Results 101 to 110 of about 37,743 (283)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Implementation of ketogenic diet in children with drug-resistant epilepsy in a medium resources setting: Egyptian experience

Epilepsy and Behavior Case Reports, 2019
Background: Even with the extensive use of ketogenic dietary therapies (KD), there still exist many areas of the world that do not provide these treatments.
Mary Gerges, Laila Selim, Marian Girgis, Amr El Ghannam, Hadeer Abdelghaffar, Ahmed El-Ayadi   +5 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Safety and tolerance of the ketogenic diet in patients with Zellweger Syndrome

Epilepsy & Behavior Reports
Zellweger Syndrome is a peroxisomal disorder that can lead to elevation of long chain fatty acids and epilepsy, which can be drug resistant. The treatment of drug resistant epilepsy can include the ketogenic diet in appropriately chosen patients ...
Borst Stephanie, Ciliberto Michael, Thati Ganganna Sreenath   +2 more
doaj   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Assessment of the Efficacy of Adhering to the Ketogenic Diet on Adipokines (Betatrophin, Endotrophin, and Meteorin-Like Protein) in Obese Women with Polycystic Ovary Syndrome

Iraqi Journal of Pharmaceutical Sciences
Obesity increases the detrimental effects on both reproductive and metabolic indicators of polycystic ovarian syndrome (PCOS). The ketogenic diet affects the outcomes of reproductive and metabolic characteristics in PCOS women.
Nazar Sattar Harbi, Waleed N. Al-Darkazali, Waeel M. Hamud   +2 more
doaj   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Global Metabolic Shifts in Age and Alzheimer's Disease Mouse Brains Pivot at NAD+/NADH Redox Sites. [PDF]

, 2019
Age and Alzheimer's disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation.
Brewer, Gregory J, Dong, Yue
core  

Spanish Ketogenic Mediterranean diet: a healthy cardiovascular diet for weight loss [PDF]

, 2008
Background Ketogenic diets are an effective healthy way of losing weight since they promote a non-atherogenic lipid profile, lower blood pressure and decrease resistance to insulin with an improvement in blood levels of glucose and insulin.
Joaquín Pérez-Guisado, Andrés Muñoz-Serrano, Ángeles Alonso-Moraga, J Pérez-Guisado, S Liu, TL Halton, W Kopp, J Pérez-Guisado, A Trichopoulou, M Osler, WC Willett, DB Panagiotakos, LA Álvarez-Sala, O Moreiras-Varela, F Perez-Jimenez, JS Perona, JA Paniagua, SD Wollin, MA Carluccio, CM Papamichael, D Mozaffarian, PD Tsitouras, LS Piers, BA Cassady, HM Dashti, M Noakes, CM Young, FL Benoit, J Pérez-Guisado, M Noakes, JJ Li, JW Beulens, JV Nielsen, G Boden, H Gin, HM Dashti, HM Dashti, JA Paniagua, E Gimeno, E Waterman, MI Covas, HM Roche, J Hartweg, M Naissides, KR Sargrad, SA McNaughton   +45 more
core   +2 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source