Results 161 to 170 of about 24,707 (302)

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Ketogenic Diet Might Regulate Autophagy of Bmscs Via Mtor Signaling Contributing to Osteoporosis in Mice

Qi Liu, Yang Zhou, Yongnong Ye, Li R, Xueli Fan, Hang Lin, Jin Zhao, Xiuhua Wu, Qingàn Zhu   +8 more
openalex   +1 more source

Beneficial effects of the ketogenic diet on nonalcoholic fatty liver disease: A comprehensive review of the literature [PDF]

, 2020
Mikiko Watanabe, Rossella Tozzi, Renata Risi, Dario Tuccinardi, Stefania Mariani, Sabrina Basciani, Giovanni Spera, Carla Lubrano, Lucio Gnessi   +8 more
openalex   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan, Eva Troyano‐Rodriguez, Jennifer Ihuoma, Sharon Negri, Rakesh Rudraboina, Aleksandra Kosmider, Shantipriya Awasthi, Priya Balasubramanian, Shannon Conley, Andriy Yabluchanskiy, Anna Csiszar, Zoltan Ungvari, Rafael de Cabo, Stefano Tarantini   +13 more
wiley   +1 more source

The Hypometabolic State of the Migraine Brain: Is a Ketogenic Diet the Answer? [PDF]

Brain Behav
Gunasekera L, Ray JC, Butzkueven H, O'Brien TJ, Hutton E, Kaul N.   +5 more
europepmc   +1 more source

Ketogenic diet modifies ribosomal protein dysregulation in KMT2D Kabuki syndrome

Erica S. Tsang, Velda X. Han, Chloe Flutter, Sarah Alshammery, Brooke A Keating, Tracey Williams, Brian Gloss, Mark E. Graham, Nader Aryamanesh, Chi Nam Ignatius Pang, Melanie Wong, David S. Winlaw, Michael Cardamone, Shekeeb S. Mohammad, Wendy Gold, Shrujna Patel, Russell C. Dale   +16 more
openalex   +1 more source

Association of the Early Response to an Oral Shape‐Shifting Superabsorbent Hydrogel Capsule With Weight Loss

Clinical Obesity, Volume 16, Issue 1, February 2026.
ABSTRACT Early response (ER) to treatment is predictive of longer‐term weight loss. In this post hoc analysis, ER to an oral shape‐shifting superabsorbent hydrogel capsule (Epitomee) combined with a lifestyle intervention was compared to placebo combined with a lifestyle intervention.
John M. Jakicic, Donna H. Ryan, Jamy D. Ard, Patrick M. O'Neil, Robert F. Kushner, Holly R. Wyatt, Harold E. Bays, Frank L. Greenway, Sharon Leonard, Yael Kenan, Eti Ganon‐Elazar, Thomas A. Wadden   +11 more
wiley   +1 more source

Classic or classical ketogenic diet? Definitions and nomenclature. [PDF]

Epileptic Disord
RamachandranNair R, Stafstrom CE, Kossoff EH.   +2 more
europepmc   +1 more source

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 287-294, February 2026.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source

Pasti ketogene diete

, 2018
Ketogena dieta postaja vse bolj priljubljena in splošno uporabljana za zniževanje telesne mase in doseganje želenih rezultatov. Sprva je bila uporabljena v zdravstvene namene, predvsem za zdravljenje trdovratne epilepsije, vendar se je zaradi učinkovitosti izkoriščanja lastne maščobe kot vira energije razširila.
openaire   +1 more source