Results 181 to 190 of about 25,226 (299)

Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) recently celebrated its 20th anniversary, reflecting two decades of major contributions to Alzheimer's research through open data sharing and longitudinal multimodal assessments. This review synthesizes 122 high‐impact studies using ADNI data or biospecimens from 2023 to mid‐2025 to ...
Dallas P. Veitch, Melanie J. Miller, Shaveta Kanoria, Paul S. Aisen, Laurel A. Beckett, Robert C. Green, Danielle J. Harvey, Clifford R. Jack Jr., William Jagust, Edward B. Lee, Kwangsik Nho, Rachel Nosheny, Ozioma C. Okonkwo, Richard J. Perrin, Ronald C. Petersen, Monica Rivera Mindt, Andrew J. Saykin, Leslie M. Shaw, Arthur W. Toga, Duygu Tosun, Susan M Landau, Michael W. Weiner, for the Alzheimer's Disease Neuroimaging Initiative   +22 more
wiley   +1 more source

The Role of the Ketogenic Diet in Lung Cancer: Current Evidence and Future Perspectives. [PDF]

Cancers (Basel)
Eleftheriadou ED, Kotoulas SC, Grammatikopoulou MG, Karakousi A, Maria A, Trimpali A, Tsalampounis X, Evangelidis P, Vamvakis A, Pataka A, Spyratos D.   +10 more
europepmc   +1 more source

Redirecting Alzheimer's disease therapeutics: Multitarget drugs and complementary non‐pharmacological strategies

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco, Jesús Andrade‐Guerrero, Nelly Jovana Pastén‐Castrejón, Chryslaine Rodríguez‐Tanty, Sofía Y Diaz‐Miranda   +4 more
wiley   +1 more source

Efficacy and safety of ketogenic diet in glioblastoma: an updated systematic review and meta-analysis. [PDF]

Neurol Sci
Firdous J, Asif AE, Haris HM, Iqbal U, Khalid M, Zahid HF, Mubarika M, Abufatima IO, Amin MHJ, Hafeez S, Jabeen F, Shahzaib M, Fatima N, Kumar N, Sen S, Hassan A.   +15 more
europepmc   +1 more source

Harnessing Gut Microbiota to Enhance Immunotherapy in NSCLC: From Mechanisms to Translational Applications

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT The gut microbiome has emerged as a pivotal regulator of immunotherapy efficacy in non‐small cell lung cancer (NSCLC), with mounting evidence demonstrating that microbial‐immune crosstalk significantly influences therapeutic responses. Current research reveals that commensal bacteria modulate host immunity through complex metabolic and ...
Liming Zhu, Jiayao Xu, Dong Niu, Xiangyu Zhang, Chunhui Jin   +4 more
wiley   +1 more source

A Ketogenic Diet for Treatment-Resistant Depression: A Randomized Clinical Trial.

JAMA Psychiatry
Gao M, Kirk M, Knight H, Lash E, Michalopoulou M, Guess N, Stevens R, Browning M, Weich S, Burnet PWJ, Jebb SA, Aveyard P.   +11 more
europepmc   +1 more source

Sexual dimorphism shapes renal metabolic adaptation to a ketogenic diet. [PDF]

Cell Rep
Kelly ME, Hoffner LA, Ramirez CB, Anica AL, Kim J, Tong G, Kim Y, Mannepalli V, Choi W, Jang KH, Alam YH, Jung S, Le J, Lopez ML, Rubtsova VI, Bae H, Chun Y, Song WS, Tamburini IJ, Schuster VL, Anton-Culver H, Lau WL, Martinez TF, Lee G, Jang C.   +24 more
europepmc   +1 more source

Familial SCN1A‐Related Epilepsy in Palestinian Siblings: Challenges of Genetic Testing in Resource‐Limited Settings: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT SCN1A‐related epilepsy may present in siblings with febrile and afebrile seizures. In resource‐limited settings, diagnosis relies heavily on clinical recognition and established criteria. Early identification and avoidance of sodium channel blockers are critical, while genetic testing, when available, supports diagnosis and family counseling.
Anwar Abu Hetta, Raghad S. Razem, Shams Shahateet, Bushra Kh. Pujee, Amal M. Shawabka, Bara M. AbuIrayyeh   +5 more
wiley   +1 more source

Ketogenic Diet and Brain Health: Cerebrovascular Mechanisms, Neuroprotection, and Translational Implications. [PDF]

Nutrients
Mózes N, Fehér Á, Csípő T, Fazekas-Pongor V, Lipécz Á, Major D, Lehoczki A, Dósa N, Pártos K, Csík B, Yi HW, Kaposvári C, Horváth K, Fekete M.   +13 more
europepmc   +1 more source

Efficacy and Safety of Adjunctive Perampanel in Young Children (7–46 Months) With Drug‐Resistant Epilepsy: A Real‐World Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This real‐world study evaluates adjunctive perampanel (PER) in young children (7–46 months) with drug‐resistant epilepsy. Results show clinically meaningful efficacy, with responder rates of up to 50% in certain syndromes. PER demonstrates a favorable safety profile, supporting its role as an effective treatment option in this age group.
Qiao Zeng, Xueqian Xia, Hao Zheng, Lu Yang, Li Jiang, Yue Hu   +5 more
wiley   +1 more source