Results 201 to 210 of about 747,960 (296)

Ketogenic Diet as an Epigenetic Therapy in SETD1B-Related Epilepsy. [PDF]

open access: yesAnn Clin Transl Neurol
Tsang E   +10 more
europepmc   +1 more source

Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review systematically examines the role of gut microbiota modulation in Alzheimer's disease, focusing on how microbial metabolites and dietary nutrients influence cognitive function and AD pathology, as well as the neuroprotective effects through the gut‐brain axis.
Binyue Xu   +6 more
wiley   +1 more source

ApoE4 as a Therapeutic Target in Epilepsy: From Pathogenic Mechanisms to Precision Medicine

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
ApoE4 acts as a key disease modifier in epilepsy by driving neuroinflammation, synaptic dysfunction, metabolic imbalance, and BBB disruption. These interacted mechanisms promote network hyperexcitability and disease progression. Targeting ApoE4 and its downstream pathways offers promising opportunities for precision therapy.
Kang Pan   +4 more
wiley   +1 more source

Integrative Multi-Omics Reveal Metabolic Reprogramming by Ketogenic Diet in Melanoma Xenografts. [PDF]

open access: yesBiomolecules
Dnyansagar R   +10 more
europepmc   +1 more source

Systematic review and meta‐analysis of lifestyle modification interventions and their impact on seizure reduction and quality of life

open access: yesEpilepsia, Volume 67, Issue 9, Page 4572-4589, September 2026.
Abstract Objective This study was undertaken to provide an overview of the research landscape and evaluate the impact of lifestyle modifications on seizure reduction and quality of life in people with epilepsy receiving standard medical treatment. Methods Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines ...
Elizabeth Spurgeon   +9 more
wiley   +1 more source

Diagnosis and management guidelines for infantile epileptic spasms syndrome around the world: A scoping review and comparative study of international approaches

open access: yesEpilepsia, Volume 67, Issue 9, Page 4600-4617, September 2026.
Abstract Objective Infantile epileptic spasms syndrome (IESS) is an epileptic encephalopathy requiring rapid diagnosis and treatment to optimize neurodevelopmental outcomes. Although multiple national and regional guidelines exist, recommendations vary.
Gozde Erdemir   +21 more
wiley   +1 more source

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