Results 71 to 80 of about 24,707 (302)

Effects of the Ketogenic Diet on Glycemic Control in Diabetic Patients: Meta-Analysis of Clinical Trials [PDF]

, 2020
Raghad A Alarim, Faris A Alasmre, Hammam A Alotaibi, Mohammed Alshehri, Sara A Hussain   +4 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Metagenomic and metabolomic analysis showing the adverse risk–benefit trade-off of the ketogenic diet

Lipids in Health and Disease
Background Ketogenic diets are increasingly popular for addressing obesity, but their impacts on the gut microbiota and metabolome remain unclear. This paper aimed to investigate how a ketogenic diet affects intestinal microorganisms and metabolites in ...
Hongyan Qiu, Chengxia Kan, Fang Han, Youhong Luo, Na Qu, Kexin Zhang, Yanhui Ma, Ningning Hou, Di Wu, Xiaodong Sun, Junfeng Shi   +10 more
doaj   +1 more source

Long-Term Ketogenic Diet Induces Metabolic Acidosis, Anemia, and Oxidative Stress in Healthy Wistar Rats

Journal of Nutrition and Metabolism, 2020
Background. Ketogenic diet has been used as supportive therapy in a range of conditions including epilepsy, diabetes mellitus, and cancer. Objective.
Aryadi Arsyad, Irfan Idris, Andi A. Rasyid, Rezky A. Usman, Kiki R. Faradillah, Wa Ode U. Latif, Zidni I. Lubis, Aminuddin Aminuddin, Ika Yustisia, Yulia Y. Djabir   +9 more
doaj   +1 more source

A two‐sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy

Epilepsia Open, EarlyView.
Abstract Objective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis. Methods Publicly accessible summary statistics on epilepsy were obtained from FinnGen and the International League Against Epilepsy Consortium.
Huaiyu Sun, Di Ma, Wuqiong Zhang, Shuai Hou, Zhiqing Chen, Xuewei Li, Hongmei Meng, Daguang Zhang   +7 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Implementation of ketogenic diet in children with drug-resistant epilepsy in a medium resources setting: Egyptian experience

Epilepsy and Behavior Case Reports, 2019
Background: Even with the extensive use of ketogenic dietary therapies (KD), there still exist many areas of the world that do not provide these treatments.
Mary Gerges, Laila Selim, Marian Girgis, Amr El Ghannam, Hadeer Abdelghaffar, Ahmed El-Ayadi   +5 more
doaj   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

The Effect of the Ketogenic Diet on Adiponectin, Omentin and Vaspin in Children with Drug-Resistant Epilepsy [PDF]

, 2022
Marcin Chyra, Wojciech Roczniak, Elżbieta Świętochowska, Magdalena Dudzińska, Joanna Oświęcimska   +4 more
openalex   +1 more source