Results 81 to 90 of about 22,654 (262)

Fecal and Serum Metabolome in Crohn’s Disease is Linked With Future Flare

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Metabolites are key mediators of various physiological functions. However, there is a lack of data linking their levels to future Crohn's Disease (CD) flares. Objective We aimed to identify systemic and gut metabolic changes that precede flare and generate metabolite‐based indexes that predict flare using a test cohort, with ...
Nina Levhar, Rotem Hadar, Tzipi Braun, Raneen Naamneh, Gilat Efroni, Bella Agranovich, Ifat Abramovich, Adi Talan Asher, Orit Picard, Adi Lahat, Doron Yablecovitch, Uri Kopylov, Rami Eliakim, Shomron Ben‐Horin, Amnon Amir, Yael Haberman, on behalf of Israeli IBD Research Nucleus (IIRN)   +16 more
wiley   +1 more source

Metagenomic and metabolomic analysis showing the adverse risk–benefit trade-off of the ketogenic diet

Lipids in Health and Disease
Background Ketogenic diets are increasingly popular for addressing obesity, but their impacts on the gut microbiota and metabolome remain unclear. This paper aimed to investigate how a ketogenic diet affects intestinal microorganisms and metabolites in ...
Hongyan Qiu, Chengxia Kan, Fang Han, Youhong Luo, Na Qu, Kexin Zhang, Yanhui Ma, Ningning Hou, Di Wu, Xiaodong Sun, Junfeng Shi   +10 more
doaj   +1 more source

Optic neuropathy in ketogenic diet. [PDF]

, 1979
C S Hoyt, Frank A. Billson
openalex   +1 more source

Polypharmacy in mice disrupts left ventricular function and structure and promotes proteome reorganisation in an age‐ and sex‐specific fashion

British Journal of Pharmacology, EarlyView.
Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran, Kevin Winardi, Scott P. Levick, Alexander Widiapradja, Gizem Gemikonakli, Susan E. Howlett, Matthew J. McKay, Mark P. Molloy, John Mach, Sarah N. Hilmer   +9 more
wiley   +1 more source

Ketonemia and Seizures: Metabolic and Anticonvulsant Effects of Two Ketogenic Diets in Childhood Epilepsy [PDF]

, 1976
Peter R. Huttenlocher
openalex   +1 more source

The Pro‐Apoptotic Effect of Glucose Restriction in NSCLC via AMPK‐Regulated Circadian Clock Gene Bmal1

Cancer Science, EarlyView.
In this study we investigate the role of the core circadian gene BMAL1 in regulating mechanisms within non‐small cell lung cancer cells, revealing that circadian rhythm disruption may represent another significant factor triggering apoptosis. ABSTRACT The circadian clock is a crucial regulator of mammalian physiology, controlling daily oscillations in ...
Tao Wei, Ying Cheng, Jierong Ge, Manting Zhu, Hong Chen, Qing Feng   +5 more
wiley   +1 more source

The influence of the ketogenic diet on the therapy of type 2 diabetes. A literature review

Journal of Education, Health and Sport
INTRODUCTION: Diabetes mellitus type 2 (DM2) is a widespread and chronic disorder with high mortality and associated morbidity rates worldwide. DM2 individuals are more susceptible to developing heart disease, cardiovascular disease, diabetic neuropathy,
Aleksandra Madej, Hanna Senat, Patrycja Grabowska, Patrycja Bolla, Aleksandra Senat, Zuzanna Marczyńska, Mateusz Dorochowicz   +6 more
doaj   +1 more source

Ketogenic Diets and their Therapeutic Potential on Breast Cancer: A Systemic Review

Cancer Management and Research, 2021
Mohammed Jemal, Tewodros Shibabaw Molla, Tadesse Asmamaw Dejenie Department of Biochemistry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Amhara, EthiopiaCorrespondence: Tadesse Asmamaw Dejenie Tel +251 ...
Jemal M, Molla TS, Asmamaw Dejenie T
doaj  

Clinical and Neurodevelopmental Characteristics of Paralogous Gain‐of‐Function Variants at GRIA2 p.Gly792 and GRIA3 p.Gly803

Clinical Genetics, EarlyView.
Key features of paralogous GRIA2 and GRIA3 gain‐of‐function variants. ABSTRACT GRIA‐related disorders arise from disease‐causing variants in GRIA1, GRIA2, GRIA3, or GRIA4 that encode α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole propionic acid (AMPA)‐type glutamate receptors (AMPARs).
Emilie Sjøstrøm, Dorota Studniarczyk, Xinyao Dou, Rebekka S. Dahl, Vincent Cruz, Heng Wang, Sandra Mercier, Wallid Deb, Thomas Besnard, Jennifer Friedman, Miriam Essid, Sana Karoui, Lamia Ben Jemaa, Thouraya Benyounes, Gaetan Lesca, Davide Tonduti, Maria Iascone, Simona Orcesi, Melanie Fradin, Christèle Dubourg, Silvia Napuri, Stuart G. Cull‐Candy, Ian D. Coombs, Mark Farrant, Allan Bayat   +24 more
wiley   +1 more source

Beyond the seizures: Ketogenic Diets in the battle against drug-resistant epilepsy

Journal of Education, Health and Sport
Introduction: Epilepsy is a chronic, non-infectious and one of the most common neurological disease. About 70 million people worldwide suffer from it and these are patients of all ages. Despite the existence of many anticonvulsants and multiple lines of
Natalia Domańska, Małgorzata Bojarska, Julia Bogucka, Anna Brzyska, Michalina Kosowska, Halina Piecewicz-Szczęsna   +5 more
doaj   +1 more source