Results 81 to 90 of about 24,707 (302)
The multiple hit model of infantile and epileptic spasms: The 2025 update
Epilepsia Open, EarlyView.Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Rapid recovery after intrathecal dexamethasone in FIRES
Epileptic Disorders, EarlyView.
João Filipe Nico +8 more
wiley +1 more source
Ketogenic diet for infantile epileptic spasms
Epilepsia Open, EarlyView.Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Safety and tolerance of the ketogenic diet in patients with Zellweger Syndrome
Epilepsy & Behavior ReportsZellweger Syndrome is a peroxisomal disorder that can lead to elevation of long chain fatty acids and epilepsy, which can be drug resistant. The treatment of drug resistant epilepsy can include the ketogenic diet in appropriately chosen patients ...
Borst Stephanie +2 more
doaj +1 more source
Predictors of etiology and drug resistance in children with new‐onset focal seizures
Epilepsia Open, EarlyView.Abstract Objective To examine the clinical features of new‐onset focal seizures in children and investigate clinical associations and predictors of underlying etiology and drug resistance. Methods Data were gathered from The Children's Hospital at Westmead admissions for patients aged 1 month to 18 years who presented with new‐onset focal seizures ...
Byoung Chan Lee +7 more
wiley +1 more source
, 2022 This paper explores a total of six research studies and will contain a literature review and proposal for further study regarding the effectiveness of the ketogenic diet as an adjuvant cancer therapy. Each study addresses a variety of different factors involved in KD implementation, ranging from effects on body composition and lipid profiles, to self ...
openaire +3 more sources
Stiripentol use in Dravet syndrome patients in the USA: Results of a real‐world study
Epilepsia Open, EarlyView.Abstract Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy with a high seizure burden and mortality risk. Stiripentol, one of the first DS‐specific therapies, received FDA approval in 2018 but its real‐world use and impact post‐approval in the USA remain insufficiently characterized.
Elaine Wirrell +11 more
wiley +1 more source
Beyond the seizures: Ketogenic Diets in the battle against drug-resistant epilepsy
Journal of Education, Health and SportIntroduction: Epilepsy is a chronic, non-infectious and one of the most common neurological disease. About 70 million people worldwide suffer from it and these are patients of all ages. Despite the existence of many anticonvulsants and multiple lines of
Natalia Domańska +5 more
doaj +1 more source
Case Reports in Nephrology, 2019 The ketogenic diet (KD) is a high-fat, adequate-protein, and low-carbohydrate diet that leads to nutritional ketosis and weight loss. It is known to induce ketosis but is not an established cause of clinically significant ketoacidosis.
Benedicta Nneoma Nnodum +3 more
doaj +1 more source
Ketogenic diet alters microglial morphology and changes the hippocampal lipidomic profile distinctively in stress susceptible versus resistant male mice upon repeated social defeat [PDF]
, 2023 Fernando Gonzàlez Ibáñez +10 more
openalex +1 more source