Results 31 to 40 of about 1,365 (197)
Synthesis and Structure−Activity Relationships of Novel 8a-Aza-8a-homoerythromycin A Ketolides
, 2016 A series of novel 6-O-substituted 8a-aza-8a-homoerythromycin A ketolides was synthesized and evaluated for in vitro antibacterial activity. Key strategic elements of the synthesis include the base-induced E−Z isomerization of 3-O-descladinosyl-6-O ...
Stjepan Mutak (1738849) +1 more
core +1 more source
Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies
ChemMedChem, Volume 21, Issue 16, 27 August 2026.A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga +5 more
wiley +1 more source
BMC Infectious Diseases, 2019 Background Solithromycin, the fourth generation of ketolides, has been demonstrated potent antibacterial effect against commonly-isolated gram-positive strains. However, Staphylococcus aureus (S.
Weiming Yao +10 more
doaj +1 more source
Analysis of Virulence Genes and Antibiotic‐Resistant Profiles of Campylobacter in Huzhou, China
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.Background Campylobacter is the leading bacterial cause of diarrheal illnesses worldwide. Campylobacter jejuni and Campylobacter coli are the main pathogens of Campylobacter infections. Drug‐resistant Campylobacter has been classified as a serious antibiotic resistance threat. Methods From 2021 to 2022, 68 Campylobacter were isolated from fecal samples
Xiaofang Wu +5 more
wiley +1 more source
Leclercia adecarboxylata Cholecystitis with Septic Shock in Immunocompetent Patient
Case Reports in Critical Care, Volume 2019, Issue 1, 2019., 2019 L. adecarboxylata is a Gram‐negative rod previously named Escherichia adecarboxylata, isolated as normal flora in the gut of animals including human stool. Most reported cases refer to immunocompromised patients with polymicrobial infections and water environments.
Nooraldin Merza +6 more
wiley +1 more source
Synthesis and Antibacterial Activity of Novel C12 Vinyl Ketolides
, 2016 A novel series of C12 vinyl erythromycin derivatives have been discovered which exhibit in vitro and in vivo potency against key respiratory pathogens. The C12 modification involves replacing the natural C12 methyl group in the erythromycin core with a ...
Alice C. Rico (2648317) +15 more
core +1 more source
APMIS, Volume 132, Issue 12, Page 1086-1095, December 2024.Azithromycin (AZM) is efficient for treatment of chronic Pseudomonas aeruginosa biofilm lung infections, despite of resistance in conventional susceptibility testing. It has been shown that planktonic P. aeruginosa are more susceptible to AZM when tested in RPMI 1640 medium. The aim of the study was to test the susceptibility to AZM of P.
Adrian Jimenez San San Mauro +2 more
wiley +1 more source
Current Perspectives on Treatment of Gram‐Positive Infections in India: What Is the Way Forward?
Interdisciplinary Perspectives on Infectious Diseases, Volume 2019, Issue 1, 2019., 2019 The emerging antimicrobial resistance leading to gram‐positive infections (GPIs) is one of the major public health threats worldwide. GPIs caused by multidrug resistant bacteria can result in increased morbidity and mortality rates along with escalated treatment cost and hospitalisation stay.
Atul P. Kulkarni +7 more
wiley +1 more source
Telitromicine. A new therapeutic option from macrolides to ketolides.
Medisur, 2004 -
Pedro Miguel Milián Vázquez. +2 more
doaj +2 more sources
, 2008 Ketolides differ from macrolides by removal of the 3-O-cladinose (replaced by a keto group), a 11,12- or 6,11-cyclic moiety and a heteroaryl-alkyl side chain attached to the macrocyclic ring through a suitable linker.
Joerg M Harms +9 more
core +1 more source