Results 1 to 10 of about 350,483 (328)
Ketone bodies: from enemy to friend and guardian angel
BMC Medicine, 2021 During starvation, fasting, or a diet containing little digestible carbohydrates, the circulating insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the major source of energy.
H. Kolb +5 more
semanticscholar +1 more source
Metabolic and Signaling Roles of Ketone Bodies in Health and Disease.
Annual review of nutrition, 2021 Ketone bodies play significant roles in organismal energy homeostasis, serving as oxidative fuels, modulators of redox potential, lipogenic precursors, and signals, primarily during states of low carbohydrate availability. Efforts to enhance wellness and
Patrycja Puchalska, P. Crawford
semanticscholar +1 more source
BMC Anesthesiology, 2023 Background It has been suggested that administration of exogenous ketone supplements (EKSs) not only increases blood ketone body levels but also decreases blood glucose level and modulates isoflurane-induced anesthesia in different rodents, such as ...
Zsolt Kovács +2 more
doaj +1 more source
Therapeutic Potential of Ketone Bodies for Patients With Cardiovascular Disease: JACC Focus Seminar.
Journal of the American College of Cardiology, 2021 Metabolic perturbations underlie a variety of cardiovascular disease states; yet, metabolic interventions to prevent or treat these disorders are sparse. Ketones carry a negative clinical stigma as they are involved in diabetic ketoacidosis.
Salva R. Yurista +5 more
semanticscholar +1 more source
SGLT2 Inhibitors and Ketone Metabolism in Heart Failure
Journal of Lipid and Atherosclerosis, 2022 Sodium-glucose cotransporter-2 (SGLT2) inhibitors have emerged as powerful drugs that can be used to treat heart failure (HF) patients, both with preserved and reduced ejection fraction and in the presence or absence of type 2 diabetes.
Huitizilihuitl Saucedo-Orozco +4 more
semanticscholar +1 more source
Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future
Sports Medicine, 2022 The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) have pleiotropic effects in multiple organs including brain, heart, and skeletal muscle by serving as an alternative substrate for energy provision, and by modulating inflammation ...
M. Evans +3 more
semanticscholar +1 more source
Baeyer-Villiger Oxidation of Ketones with Hydrogen peroxide in the presence of Nano Zinc oxide [PDF]
شیمی کاربردی روز, 2018 In this work, a new application of nano zinc oxide in Baeyer-Villiger oxidation of ketones with hydrogen peroxide has been introduced. The capability of nano zinc oxide as a heterogeneous catalyst on the basis of of its very small size and large surface ...
Fatemeh Doragi, Mohammad Javaherian
doaj +1 more source
Effects of Exogenous Ketone Supplementation on Blood Glucose: A Systematic Review and Meta-Analysis.
Advances in Nutrition, 2022 Recently developed ketone (monoester or salt) supplements acutely elevate blood β-hydroxybutyrate (BHB) exogenously without prolonged periods of fasting or carbohydrate restriction.
K. Falkenhain +3 more
semanticscholar +1 more source
Ruthenacycles and Iridacycles as Transfer Hydrogenation Catalysts
Molecules, 2021 In this review, we describe the synthesis and use in hydrogen transfer reactions of ruthenacycles and iridacycles. The review limits itself to metallacycles where a ligand is bound in bidentate fashion to either ruthenium or iridium via a carbon–metal ...
Vincent Ritleng, Johannes G. de Vries
doaj +1 more source
Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases
International Journal of Molecular Sciences, 2020 Under normal physiological conditions the brain primarily utilizes glucose for ATP generation. However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for the brain.
N. Jensen +3 more
semanticscholar +1 more source