Results 41 to 50 of about 331,332 (337)

Heterogenisation of ketone catalysts within mesoporous supports for asymmetric epoxidation

, 2013
The synthesis of the first mesoporous silica (150 Å) anchored carbohydrate-derived chiral ketone is described. This new heterogeneous catalyst has been shown to be effective in the asymmetric epoxidation of olefins by oxone.
Adam, Aggarwal, Amadori, Amadori, Armstrong, Beckwith, Bellamy, Bloch, Caprio, Chadwick, Cho, Corey, Denmark, Denmark, Denmark, Dondoni, Farina, Frohn, Goeddel, Heitbaum, Hutchings, Jacobsen, Johansson Seechurn, Johnson, Johnson, Jones, Katsuki, McMorn, Page, Page, Pedragosa-Moreau, Raja, Raynor, Ren, Romesberg, Ross, Sartori, Shephard, Shu, Song, Stearman, Thomas, Thomas, Thomas, Tian, Tian, Tian, van den Broek, Wang, Wang, Wang, Wang, Wong, Wong, Xia, Xiong, Xuereb, Yang, Yang, Zhao, Zhu   +60 more
core   +1 more source

The clinical significance of the arterial ketone body ratio as an early indicator of graft viabilityin human liver transplantation [PDF]

, 1991
Arterial ketone body ratio (AKBR) was measured sequentially in 84 liver transplantations (OLTx). These transplantation procedures were classified into 3 groups with respect to graft survival and patient condition at the end of the first month (Group A ...
Asonuma, K, Okamoto, R, Ozawa, K, Selby, R, Starzl, TE, Takaya, S, Todo, S, Yamamoto, Y, Yokoyama, T   +8 more
core   +1 more source

Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones [PDF]

, 2013
2-Substituted oxetan-3-ones can be prepared in good yields and enantioselectivities (up to 84% ee) by the metalation of the SAMP/RAMP hydrazones of oxetan-3-one, followed by reaction with a range of electrophiles that include alkyl, allyl, and benzyl ...
Beasley, Benjamin, Clarkson, Guy J., Geden, Joanna V., Shipman, Michael   +3 more
core   +1 more source

Case report: Ketogenic diet acutely improves cognitive function in patient with Down syndrome and Alzheimer’s disease

Frontiers in Psychiatry, 2023
Ketogenic diets have a century-long history as a therapeutic tool to treat intractable epilepsy. Recently, a renewed interest in neuroketotherapeutics has arisen, with ketogenic diets being explored for the treatment of neurodegenerative diseases such as
Annette Bosworth, Vyvyane Loh, Blackjack N. Stranahan, Christopher M. Palmer   +3 more
doaj   +1 more source

Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects

Frontiers in Nutrition
IntroductionThe brain uses ketones, mainly 3-hydroxybutyrate (3-HB), as an alternative energy source. Therefore, oral intake of 3-HB may help maintain brain health.
Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama   +12 more
doaj   +1 more source

Nutritional Ketoacidosis During Incremental Exercise in Healthy Athletes

Frontiers in Physiology, 2019
Purpose: Ketosis, achieved through ingestion of ketone esters, may influence endurance exercise capacity by altering substrate metabolism. However, the effects of ketone consumption on acid-base status and subsequent metabolic and respiratory ...
David J. Dearlove, Olivia K. Faull, Olivia K. Faull, Edward Rolls, Kieran Clarke, Pete J. Cox   +5 more
doaj   +1 more source

Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate

Frontiers in Pharmacology, 2020
The inverse relationship of plasma bilirubin levels with liver fat accumulation has prompted the possibility of bilirubin as a therapeutic for non-alcoholic fatty liver disease. Here, we used diet-induced obese mice with non-alcoholic fatty liver disease
Terry D. Hinds, Justin F. Creeden, Darren M. Gordon, Donald F. Stec, Matthew C. Donald, David E. Stec   +5 more
doaj   +1 more source

2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle

Cells, 2022
Cachexia is characterized by progressive weight loss accompanied by the loss of specific skeletal muscle and adipose tissue. Increased lactate production, either due to the Warburg effect from tumors or accelerated glycolysis effects from cachectic ...
Lulu Wei, Ranran Wang, Junaid Wazir, Kai Lin, Shiyu Song, Li Li, Wenyuan Pu, Chen Zhao, Yong Wang, Zhonglan Su, Hongwei Wang   +10 more
doaj   +1 more source

Anti-oxidant and anti-inflammatory activity of ketogenic diet. New perspectives for neuroprotection in alzheimer’s disease [PDF]

, 2018
The ketogenic diet, originally developed for the treatment of epilepsy in non-responder children, is spreading to be used in the treatment of many diseases, including Alzheimer’s disease.
Bonucci, Alessio, Businaro, Rita, Corsi, Mariangela, Maggi, Elisa, Pinto, Alessandro   +4 more
core   +1 more source

Feasibility of Interstitial Fluid Ketone Monitoring with Microneedles

Metabolites, 2022
Diabetic ketoacidosis (DKA) is one of the most dangerous and costly complications of diabetes, accounting for approximately 50% of deaths in diabetic individuals under 24 years.
Robert M. Taylor, Justin T. Baca
doaj   +1 more source