Results 11 to 20 of about 52,379 (262)
Ketone bodies in epilepsy [PDF]
Journal of Neurochemistry, 2012 J. Neurochem.(2012)121, 28–35.AbstractSeizures that are resistant to standard medications remain a major clinical problem. One underutilized option for patients with medication‐resistant seizures is the high‐fat, low‐carbohydrate ketogenic diet. The diet received its name based on the observation that patients consuming this diet produce ketone bodies (
Melanie A, McNally, Adam L, Hartman
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Cell Discovery, 2022 Neonatal heart undergoes metabolic conversion and cell cycle arrest preparing for the increased workload during adulthood. Herein, we report that neonatal ketone body elevation is a critical regulatory factor for postnatal heart development.
Danyang Chong +16 more
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Systemic Ketone Replacement Does Not Improve Survival or Cancer Cachexia in Mice With Lung Cancer
Frontiers in Oncology, 2022 Cachexia is a debilitating comorbidity affecting many lung cancer patients. We have previously found that cachectic mice with lung cancer have reduced serum ketone body levels due to low PPARα activity in the liver.
Henning Tim Langer +11 more
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Ketone body oxidation increases cardiac endothelial cell proliferation
EMBO Molecular Medicine, 2022 Blood vessel formation is dependent on metabolic adaption in endothelial cells. Glucose and fatty acids are essential substrates for ATP and biomass production; however, the metabolism of other substrates remains poorly understood.
Eva‐Maria Weis +13 more
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Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy [PDF]
, 2011 Background: Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect.
Maurer, Gabriele D. +8 more
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Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study [PDF]
, 2020 BACKGROUND: Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system in young adults that may lead to progressive disability.
Bahr, Lina Samira +12 more
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Molecular Metabolism, 2021 Objective: Throughout the last decade, interest has intensified in intermittent fasting, ketogenic diets, and exogenous ketone therapies as prospective health-promoting, therapeutic, and performance-enhancing agents.
David B. Stagg +6 more
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Archives of Medical Science – Atherosclerotic Diseases, 2021 Ketone bodies are low chain organic substances with four carbon atoms, with β-hydroxybutyric acid and acetone being the main ketone bodies in blood circulation. Under physiological conditions their levels are low while during conditions of oxidative stress, such as exercise, fasting state and acute illness, ketone body levels are increased.
Papazafiropoulou, Athanasia K. +2 more
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Another D in MUDPILES? A Review of Diet-Associated Nondiabetic Ketoacidosis. [PDF]
, 2018 Ketogenic diet or very-low-carbohydrate diet gained widespread popularity in the 1990s due to their favorable effects on weight loss and diabetes among others with good short-term safety data.
Ammar Abdullah, Hafez Mohammad +4 more
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The clinical significance of the arterial ketone body ratio as an early indicator of graft viabilityin human liver transplantation [PDF]
, 1991 Arterial ketone body ratio (AKBR) was measured sequentially in 84 liver transplantations (OLTx). These transplantation procedures were classified into 3 groups with respect to graft survival and patient condition at the end of the first month (Group A ...
Asonuma, K +8 more
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