Results 201 to 210 of about 52,379 (262)

Peri‐operative management of diabetes mellitus: a multidisciplinary consensus statement from the Association of Anaesthetists and the Joint British Diabetes Societies for Inpatient Care group

Anaesthesia, EarlyView.
Summary Introduction Surgery in patients with diabetes mellitus is associated with increased morbidity and mortality compared with those who do not have diabetes mellitus. This is likely multifactorial and could be attributed to organisational issues; dysglycaemia; hospital‐acquired diabetic ketoacidosis; errors with insulin prescribing and ...
Nicholas A. Levy, Kariem El‐Boghdadly, Dileep N. Lobo, Daniel J. Stubbs, Parizad Avari, Donal Buggy, Claire Frank, Kim Howson, Jinty Moffett, Emma Morris, Omar G. Mustafa, Glynn Nash, Pádraig Ó Scanaill, Sarah Procter, Gerry Rayman, Kim Russon, Caroline Thomas, Sarah Tinsley, Allan Xu, Ketan Dhatariya   +19 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Accuracy (Trueness and Precision) of the Calibrated Intraoral Scan Protocol: An In Vitro Comparison of Three Scan Calibrator Designs In an Edentulous Implant Model

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To introduce a universal scan calibrator (SC) and to evaluate its accuracy in the calibrated intraoral scan protocol (CISP) by comparison with two previously published SCs. Materials and Methods Three SCs were evaluated on an edentulous implant model containing six scan bodies (SBs) positioned at the screw‐retained abutment (SRA ...
Shengtao Yang, Chenyi Zhang, Yan Bao, Shuo Wang, Lei Chi, Li Yue, Quan Yuan, Junying Li   +7 more
wiley   +1 more source

Effect of interdisciplinary obesity care on metabolic markers and body weight in people with type 2 diabetes in a rural setting: A randomised controlled trial

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet, Iain K. Robertson, Sharon P. Luccisano, Michelle L. Kilpatrick   +3 more
wiley   +1 more source

Can the Diabetes Eating Problem Survey‐Revised (DEPS‐R) reliably identify eating disorder diagnosis in women with type 1 diabetes?

Diabetic Medicine, EarlyView.
Abstract Aims The objective of this study was to evaluate the Diabetes Eating Problems Survey‐Revised (DEPS‐R) against the Eating Disorder Diagnostic Interview (EDDI). Specific aims were to (1) assess the ability of the DEPS‐R to identify Diagnostic and Statistical Manual‐5 (DSM‐5) eating disorders, including sensitivity and specificity of the current ...
Severina Haugvik, Mareille H. C. L. Hennekes, Maartje de Wit, Elena Toschi, Christopher D. Desjardins, Torild Skrivarhaug, Knut Dahl‐Jørgensen, Eric Stice, Line Wisting   +8 more
wiley   +1 more source

Decision accuracy of simultaneously used real‐time CGM versus intermittently scanned CGM around exercise in type 1 diabetes: A secondary analysis of the ULTRAFLEXI‐1 study

Diabetic Medicine, EarlyView.
Abstract Aims Continuous glucose monitoring (CGM) systems have become important technologies to improve glycaemia in people with type 1 diabetes (T1D). However, it has been shown that during rapid glucose change, sensor performance can deteriorate.
Sabrina Sanfilippo, Alexander Müller, Felix Aberer, Faisal Aziz, Harald Kojzar, Caren Sourij, Ulrike Leb‐Stöger, Philipp Birnbaumer, Peter N. Pferschy, Norbert Tripolt, Harald Sourij, Othmar Moser   +11 more
wiley   +1 more source

Diabetes management in people undergoing metabolic‐bariatric surgery: A guideline from the Joint British Diabetes Societies for Inpatient Care (JBDS‐IP) Group

Diabetic Medicine, EarlyView.
Abstract The global prevalence of obesity and diabetes continues to rise, with metabolic‐bariatric surgery recognised as an effective intervention for obesity and type 2 diabetes, offering potential for type 2 diabetes remission and improved glycaemic control. This guideline, developed by the Joint British Diabetes Societies for Inpatient Care (JBDS‐IP)
Jeffrey W. Stephens, Ketan Dhatariya, Andrew J. Beamish, Dimitri J. Pournaras, Alexander D. Miras, Nader Raafat, Georgia Noble‐Bell, Rachel Cadwallader Buckland, Omar G. Mustafa   +8 more
wiley   +1 more source

Rethinking control‐IQ+ technology: Simple strategies for easy optimization

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Control‐IQ+ is an automated insulin delivery (AID) algorithm approved for people with type 1 diabetes aged 2+ years and adults aged 18+ years with type 2 diabetes. While numerous publications support improved glycaemia and quality of life for people with diabetes, this practice paper is intended to encourage uptake for healthcare professionals
Viral N. Shah, Pratik Choudhary, Ilana Halperin, Ivana Rabbone, Dessi P. Zaharieva, Laurel Messer   +5 more
wiley   +1 more source

An international consensus on screening and monitoring early‐stage type 1 diabetes: A roadmap to European implementation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease that results in loss of insulin‐secreting pancreatic β‐cells in the islets of Langerhans. A diagnosis of T1D is typically associated with children and adolescents, yet half of all diagnoses of T1D are made in adults.
Sufyan Hussain, Timothy Tree, Chantal Mathieu, Tomasz Klupa, Anna‐Kaisa Tuomaala, Maartje de Wit, Olga Kordonouri, Katarina Braune, Jaivir Pall, Luis Castano, Rachel E. J. Besser, Júlia Galhardo, Francesca Ulivi, Emanuele Bosi, Uroš Bogdanovic, Coralie Alabert, Tadej Battelino   +16 more
wiley   +1 more source