Results 41 to 50 of about 34,264 (258)
Correlations between electrochemical behaviors and DNA photooxidative properties of non-steroïdal anti-inflammatory drugs and their photoproducts [PDF]
Alkali-labile lesion to DNA photosensitized, via an electron transfer mechanism, by three non-steroidalanti-inflammatorydrugs (NSAIDs), ketoprofen, tiaprofenic acid and naproxen and their photoproducts during drug photolysis, was investigated using 32P ...
Chouini-Lalanne, Nadia +6 more
core +2 more sources
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen +5 more
wiley +1 more source
Formation of Ketoprofen-Malonic Acid Cocrystal by Solvent Evaporation Method
The purpose of this work was to explore the formation of ketoprofen-malonic acid cocrystal by solvent evaporation method. Early detection of cocrystal formation was conducted by hot stage microscopy and solid-liquid phase diagram. Cocrystal were prepared
Yudi Wicaksono +2 more
doaj +1 more source
Targeted monitoring for human pharmaceuticals in vulnerable source and final waters [PDF]
A range of pharmaceuticals has been detected in soils, surface waters and groundwaters across the world. While the reported concentrations are generally low (i.e. sub μg l-1 in surface waters), the substances have been observed throughout the year across
Bersuder, Phillipe +6 more
core
Photoinduced Boron‐Catalyzed Direct α‐Aminoxylation of Carboxylic Acids
A boron‐catalyzed α‐aminoxylation of carboxylic acids enables rapid access to sterically congested α‐(aminoxy)carboxylic acids. Photoexcited diboron enediolates transfer energy to O‐sulfonylhydroxylamines, triggering SO bond cleavage to generate N‐oxyl radicals.
Tsubasa Oyama +5 more
wiley +1 more source
Polyelectrolyte multilayer assembly bearing ketoprofen for transdermal delivery [PDF]
A novel microencapsulation technology based on layer-by-layer assembly has been extensively studied and used for controlled delivery of drug microcrystal having poor aqueous solubility and low bioavailability.
Preeti Yadav +2 more
core +2 more sources
A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands
A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova +15 more
wiley +1 more source
The study was aimed at increasing solubility and dissolution rate of ketoprofen by using multicomponent crystallization approach with nicotinamide as additional material.
Yudi Wicaksono +2 more
doaj +1 more source
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source

