Results 21 to 30 of about 12,190 (176)

Dendritic macromolecules as nano-scale drug carriers: Phase solubility, in vitro drug release, hemolysis and cytotoxicity study

open access: yesAsian Journal of Pharmaceutical Sciences, 2015
Potential of nanoscale triazine based dendritic macromolecules G1, G2 and G3 as solubility enhancers of drug was investigated. Effect of pH, concentration and generation of synthesized dendritic macromolecules on solubility of ketoprofen was studied.
Pravinkumar M. Patel   +3 more
doaj   +1 more source

In vitro kinetic release study of ketoprofen enantiomers from alginate metal complexes

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background To explore the release behavior of ketoprofen enantiomers from alginate-metal-complexes. Five mathematical models of drug release kinetics were investigated.
Ghaidaa Alkhayer   +2 more
doaj   +1 more source

Effect of oral ketoprofen on pain perception during copper IUD insertion among parous women: A randomized double-blind controlled trial

open access: yesMiddle East Fertility Society Journal, 2018
Objective: The study aims to evaluate the analgesic effect of oral ketoprofen prior to copper intrauterine device (IUD) insertion on pain perception during the insertion procedure.Study design: A randomized double-blind controlled trial (Clinical Trials.
Ahmed M. Abbas   +3 more
doaj   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

open access: yesAdvanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

IN VITRO IRREVERSIBLE BINDING AND DEGRADATION OF (R)- AND (S)-KETOPROFEN GLUCURONIDES TO PLASMA PROTEINS [PDF]

open access: yesMalaysian Journal of Pharmaceutical Sciences, 2007
This study describes the in vitro degradation studies of the diastereomeric ketoprofen glucuronides, under physiological conditions (pH 7.4, 37°C, (R)-ketoprofen glucuronide t½ = 30 min, (S)-ketoprofen glucuronide t½ = 70 min) and the irreversible ...
PETER J. HAYBALL, KELLIE L. TUCK
doaj  

Formation of Ketoprofen-Malonic Acid Cocrystal by Solvent Evaporation Method

open access: yesIndonesian Journal of Chemistry, 2017
The purpose of this work was to explore the formation of ketoprofen-malonic acid cocrystal by solvent evaporation method. Early detection of cocrystal formation was conducted by hot stage microscopy and solid-liquid phase diagram. Cocrystal were prepared
Yudi Wicaksono   +2 more
doaj   +1 more source

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira   +3 more
wiley   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian   +4 more
wiley   +1 more source

Iron‐Photocatalyzed Ligand‐to‐Metal Charge Transfer‐Driven Decarboxylative Giese‐Type Reactions Under Mild Conditions

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Iron‐photocatalyzed LMCT enables decarboxylative hydroalkylation of Michael acceptors (Giese‐type reaction) under mild conditions. Using tailored ligands and a sterically hindered very mild aniline base, diverse carboxylic acids efficiently couple with sensitive Michael acceptors, including maleimides.
Luca Mareen Denkler   +9 more
wiley   +1 more source

EFFECT OF CERTAIN FACTORS ON BINDING OF KETOPROFEN TO HUMAN SERUM ALBUMIN

open access: yesZagazig Journal of Pharmaceutical Sciences, 2001
A study was made to investigate the interaction of Ketoprofen with human serum albumin (HSA) in isotonic Sorensen's phosphate buffer of pH 7.4 at 37°C.
Mahmoud Mahdy
doaj   +1 more source

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