Animal Research and One Health, EarlyView.(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng +6 more
wiley +1 more source
Nivolumab-induced fulminant diabetic ketoacidosis followed by thyroiditis [PDF]
, 2018 Five days following the 3rd cycle of nivolumab, a monoclonal antibody, which acts as immune checkpoint inhibitor against the programmed cell death protein-1, for metastatic lung adenocarcinoma, a 56-year-old woman presented at the hospital critically ill.
Baker, E +6 more
core +2 more sources
Hepatic gluconeogenesis and regulatory mechanisms in lactating ruminants: A literature review
Animal Research and One Health, EarlyView.phosphoenolpyruvate carboxy kinase, FBP1, and glucose‐6‐phosphatase are key rate‐limiting enzymes that determine the efficiency of gluconeogenesis. The main substrate for gluconeogenesis in the liver of ruminants is propionate, which provides more than 60% of the carbon source for gluconeogenesis.
Guoyan Wang +5 more
wiley +1 more source
Pathway analysis of plasma different metabolites for dairy cow ketosis
Italian Journal of Animal Science, 2016 Metabolic profiling was performed using nuclear magnetic resonance (NMR)-based metabolomics to explore panoramic changes in ketosis metabolism in dairy cows, and to further understand changes in metabolites when ketosis occurred.
Yanhui Wang +5 more
doaj +1 more source
Induced Ketosis as a Treatment for Neuroprogressive Disorders: Food for Thought?
International Journal of Neuropsychopharmacology, 2020 Induced ketosis (or ketone body ingestion) can ameliorate several changes associated with neuroprogressive disorders, including schizophrenia, bipolar disorder, and major depressive disorder.
G. Morris +6 more
semanticscholar +1 more source
Metabolic processes in calves and their correction in the conditions of Kyrgyzstan [PDF]
BIO Web of ConferencesThis scientific work shows the results of using a new mineral-vitamin premix “Ketgib-2” and an anti-ketosis-adaptogenic solution for metabolic disorders in local breed calves.
Nogoibaev Mucanbet +5 more
doaj +1 more source
Management of diabetic ketoacidosis in adult inpatients: A retrospective analysis of rates of hypoglycaemia with variable-rate and fixed-rate intravenous insulin infusion protocols. [PDF]
Diabet MedAbstract Aims To compare variable‐rate intravenous insulin infusion (VRIII) to fixed‐rate intravenous insulin infusion (FRIII) on the incidence of hypoglycaemia during DKA management. Secondary outcomes were time to resolution of ketosis and hospital length of stay.
Baddock S +4 more
europepmc +2 more sources
Ketosis in Hepatic Glycogenosis [PDF]
Archives of Disease in Childhood, 1972 The occurrence of ketosis in 41 patients with liver glycogenosis and a control group of 22 children was investigated. Fasting ketosis was present in children with a deficiency of the debranching enzyme system and in young children with a deficiency of the phosphorylase system, but never in patients with a glucose-6-phosphatase deficiency.
J. Fernandes, N. A. Pikaar
openaire +3 more sources
2-pentanone production from hexanoic acid by Penicillium roqueforti from blue cheese:is this the pathway used in humans? [PDF]
, 2014 Production of 2-pentanone, a methylketone, is increased in fasting ketotic humans. Its origin is unknown. We hypothesised that it is formed via β-oxidation of hexanoic acid by the peroxisomal pathway proposed for methylketone-producing fungi and yeasts ...
Mills, Graham A., Walker, Valerie
core +2 more sources
Ketosis an Old Story Under a New Approach
, 2020 Ketosis, characterized by high concentrations of ketone bodies in the blood, urine, and milk, affects a considerable number of cows immediately after calving.
Guanshi Zhang, B. Ametaj
semanticscholar +1 more source