Results 151 to 160 of about 23,218 (270)

Table_1_Association Between Circulating Proprotein Convertase Subtilisin/Kexin Type 9 Concentrations and Cardiovascular Events in Cardiovascular Disease: A Systemic Review and Meta-Analysis.DOCX

open access: green, 2021
Jiahui Liu (724342)   +6 more
openalex   +2 more sources

Cardiovascular Dysfunction in Polycystic Ovary Syndrome: Mitochondrial and Inflammatory Mechanisms

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder that significantly increases cardiovascular disease (CVD) risk in women. While insulin resistance and dyslipidemia are established contributors, growing evidence highlights mitochondrial dysfunction and chronic low‐grade inflammation as central drivers of cardiovascular ...
Olabimpe Caroline Badejogbin   +8 more
wiley   +1 more source

Leptin, Resistin, and Proprotein Convertase Subtilisin/Kexin Type 9 [PDF]

open access: yesThe American Journal of Pathology, 2020
Chiara Macchi   +13 more
openaire   +1 more source

Epigenetic Regulation of ITGB7 Promotes Coronary Heart Disease via Immune and Metabolic Pathways: A Multimodal Mendelian Randomization Study

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Background Coronary heart disease (CHD) is a leading cause of cardiovascular mortality worldwide, with its pathogenesis being complex and not yet fully understood. The rapid development of genomics, especially in epigenetic research, has provided essential tools for identifying new pathogenic targets. This study is aimed at systematically exploring the
Junchi Guo   +4 more
wiley   +1 more source

The Efficacy and Safety of Four Novel PCSK9 Monoclonal Antibodies in Patients With Hypercholesterolemia: A Systematic Review With Network Meta‐Analysis and Trial Sequential Analysis

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Aim This network meta‐analysis (NMA) evaluated four novel proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies for hypercholesterolemia management, comparing their lipid‐lowering efficacy and safety. Methods We systematically identified randomized controlled trials employing the frequentist NMA method to assess reductions in low ...
Sihua Wang   +3 more
wiley   +1 more source

Polymorphisms in the proprotein convertase subtilisin/kexin type 9 gene in clinically diagnosed patients with familial hypercholesterolemia. [PDF]

open access: yesRev Assoc Med Bras (1992)
Costa ALDS   +8 more
europepmc   +1 more source

Lipoprotein(a) in Familial Hypercholesterolemia With Proprotein Convertase Subtilisin/Kexin Type 9 (<i>PCSK9</i>) Gain-of-Function Mutations

open access: diamond, 2015
Hayato Tada   +9 more
openalex   +2 more sources

Astaxanthin Reverses Oxidative Stress‐Induced Dysfunction in Human Periodontal Ligament Stem Cells by Activating the Nrf2/ARE Pathway

open access: yesStem Cells International, Volume 2026, Issue 1, 2026.
Background Oxidative stress plays a crucial role in the pathogenesis of periodontitis and compromises the regenerative potential of human periodontal ligament stem cells (hPDLSCs). Astaxanthin (ASX), a potent natural antioxidant with both lipophilic and hydrophilic properties, has been shown to scavenge reactive oxygen species (ROS).
Jingwen Chi   +8 more
wiley   +1 more source

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