Migrasome-mediated clearance of PLK4: a novel mechanism for centrosome homeostasis and tumor targeting. [PDF]
EBioMedicineZhao Z, Song Y.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham +11 more
wiley +1 more source
Water-dispersible perovskite nanocrystals: synthesis strategies, ion sensing applications, and future prospects. [PDF]
RSC AdvLu Z, Weng X, Yang J, Fan H.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
pH Driving the Self-Assembly of Hydrolyzed Edible Dock Protein and Myricetin. [PDF]
FoodsWang X, Arshad A, Liang J.
europepmc +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Fabrication and Characterization of Zein/Sodium Alginate Nanoparticles Loaded with Oxyresveratrol: Formation Mechanism, Molecular Dynamics Insights, and In Vitro Antioxidant Capacity. [PDF]
Micromachines (Basel)Luo X, Du Z.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan +12 more
wiley +1 more source
Encapsulation of carbon dots in medicinal chemistry: a comprehensive review of recent advances and applications. [PDF]
RSC AdvMohammed SJ +6 more
europepmc +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Advanced Healthcare Materials, EarlyView.Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source