Results 71 to 80 of about 505,343 (301)

Performance and sustainability evaluation of rural digitalization and its driving mechanism: evidence from Hunan province of China

Frontiers in Environmental Science, 2023
Quantitatively measuring rural digitalization performance and development sustainability, identifying their key influencing factors and figuring out their driving mechanisms are of great value to policy design for rural revitalization and management ...
Zhipeng Xing, Sidong Zhao, Di Wang, Di Wang   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

FACTORS INFLUENCING THE PERFORMANCE OF KEY ACCOUNT MANAGERS IN THE INDONESIAN BANKING INDUSTRY

International Journal of Application on Economics and Business
The banking business stands as a service-oriented enterprise rooted in the principle of trust, where the banking sector heavily relies on service delivery to manage customer trust, thereby ensuring that clients continue to entrust their funds and financial matters to a bank. Within the realm of banking, Key Account Management (KAM) plays a crucial role
Zipora Pratama, Sekarsyifa Sesarea, Meyriana Kesuma, Fajar Fadillah, Andre Williams   +4 more
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Explainable Artificial Intelligence and Legal Ethos: Developing Key Performance Indicators for ‘G20 Giants’

Journal of Digital Technologies and Law
Objective: to study the “right to explanation” in the context of the PEEC doctrine (public interest, environmental sustainability, economic development, criminal justice) in order to develop key performance indicators reflecting the socio-cultural ...
N. Bhatt, J. N. Bhatt
doaj   +1 more source

PROJECT-ORIENTED APPROACH, AS THE RELATIONSHIP MANAGEMENT TECHNIQUES WITH COMPANY STRATEGY

Sovremennye Issledovaniâ Socialʹnyh Problem, 2015
In the development of modern methods of project management, it is evident that project-oriented approach is not in any individual cases, but quite the contrary – is increasingly becoming the standard way of managing the company.
Artem Anatolievich Gribin
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

CHARACTERISTICS OF THE INDICATORS OF FINANCIAL PERFORMANCE USED IN THE CONTROLLING [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2017
Financial Performance a center of responsibility shall be measured on the basis of specific indicators nature of the center. In the conditions of a powerful descentralizari, most datacenters become centers of investments.
LOREDANA CIURLĂU
doaj  

Robustness of the Multi-Attribute Utility Model for Bridge Maintenance Planning

The Baltic Journal of Road and Bridge Engineering, 2018
Optimisation of maintenance planning is an essential part of bridge management. With the purpose to support maintenance planning, a multi- objective decision-making model is introduced in this paper.
Zaharah Allah Bukhsh, Irina Stipanovic, Sandra Skaric Palic, Giel Klanker   +3 more
doaj   +1 more source