Results 41 to 50 of about 103,973 (310)

Collaboration : A key competence for competing in the 21st Century [PDF]

open access: yes, 2008
It is now an accepted fact that in the 21st century competition will be between networks of organisations and individuals, which efficiently and effectively integrate their competencies and resources in order to compete in a global economy (Bititci et al, 2004). Similarly the SME’2000 conference, which was held in Bologna, conclude that “SMEs belonging
Bititci, Umit   +3 more
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Key competencies in education for sustainable development: A valuable framework for enhancing plant awareness

open access: yesPlants, People, Planet
Societal Impact Statement Lack of plant awareness represents a significant phenomenon characterized by the underestimation of plants, with clear implications for sustainability.
Alexandros Amprazis   +1 more
doaj   +1 more source

STAGES OF MODERNISATION OF THE CONTENT OF PRIMARY SCHOOL EDUCATION: UKRAINIAN EXPERIENCE

open access: yesEducation: Modern Discourses, 2018
The article highlights the Ukrainian experience of modernising the content of primary education under state independence of Ukraine. Based on the dynamics of the introduction of the State Standards for Primary Education and of a competence-based approach,
Оleksandra Savchenko
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The Development and Psychometric Properties of the «Self-Regulated Knowledge Scale - University» (SRKS-U)

open access: yesJournal of Educational, Cultural and Psychological Studies, 2015
Cognitive self-regulation refers to the mental processes that students adopt with the aim of adapting and changing their processes of cognition and that can lead to positive results in terms of learning.
Sara Manganelli   +3 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

METHODOLOGY OF ENTERPRISE’S RESOURCE STRATEGY STRUCTURAL ELEMENTS: COMPETITIVE RATING

open access: yesВестник СибАДИ, 2018
Introduction. The article deals with the basic structural elements of strategic planning at the motor transport enterprises, especially in the conditions of the international political processes related to the global crisis and the anti-Russian sanctions,
S. N. Chepeleva
doaj   +1 more source

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