Results 221 to 230 of about 6,293,788 (277)
There is a lock for every key [PDF]
Nature Chemical Biology, 2021 Chemoproteomics-enabled identification of the targets of a hydroxylated cholesterol metabolite, 20(S)-hydroxycholesterol, reveals it to be the first reported endogenous ligand of the sigma-2 receptor, a drug target for neurodegeneration and neuropathic pain.
Weizhi Yu, Jeremy M. Baskin
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DK Lock: Dual Key Logic Locking Against Oracle-Guided Attacks
IEEE International Symposium on Quality Electronic Design, 2023The semiconductor industry must deal with different hardware threats like piracy and overproduction as a result of outsourcing manufacturing. While there are many proposals to lock the circuit using a global protected key only known to the designer ...
Jordan Maynard, Amin Rezaei
semanticscholar +1 more source
Nature, 2010 New functional materials can in principle be created using colloids that self-assemble into a desired structure by means of a programmable recognition and binding scheme. This idea has been explored by attaching 'programmed' DNA strands to nanometre- and micrometre- sized particles and then using DNA hybridization to direct the placement of the ...
William T. M. Irvine +3 more
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Imaging Hg2+-induced oxidative stress by NIR molecular probe with "dual-key-and-lock" strategy.
Analytical Chemistry, 2020Mercury (Hg) is considered as an extremely toxic heavy metal which is extremely harmful to both the human body and environment. In addition, Hg2+-induced oxidative stress also exerts a crucial role to play in pathophysiological mechanisms of mercury ...
Xiaopeng Yang +7 more
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Synthesis of ‘dual-key-and-lock’ drug carriers for imaging and improved drug release
Nanotechnology, 2020In this work, a ‘dual-key-and-lock’ drug carrier was designed to respond to the tumor microenvironment (TME). A core–shell Fe-MOF@ZIF-8 was synthesized, with ZIF-8 as the shell (the first lock) to encapsulate catalase (CAT), and the Fe metal–organic ...
Haiqing Gao +9 more
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Locks and keys to the boardroom
Gender in Management: An International Journal, 2003This paper reports an interview study with 12 directors in a major international telecommunications company, to identify the career paths which they took to reach board level in their organisation. The aim was to ascertain whether there were gender differences in the career facilitators and barriers met en route to the top.
Susan Vinnicombe, Val Singh
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Best Practices: To Lock or Not to Lock Patients'Rooms: The Key to Autonomy?
Psychiatric Services, 2008Many patients with schizophrenia experience prominent negative symptoms. Functional impairment often results in patients who remain in their rooms for most of the day. It has thus become common practice in many psychiatric wards to lock patients' rooms during much of the morning and afternoon hours to encourage participation in ward activities and ...
Anne-Marie Ulman +3 more
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Key-lock type mini-sternotomy: an alternative approach for adult cardiac operations.
Heart Surgery Forum, 2015An alternative technique for minimally invasive aortic valve replacement and atrial septal defect repair is described. After a 5-cm skin incision, a key-lock type sternotomy is made.
M. Dumantepe, A. Tarhan, A. Ozler
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Journal of Neurology, Neurosurgery & Psychiatry, 2012
This case demonstrates two uncommon conditions presenting in a single patient. A 47-year-old male with a history since childhood of generalised tonic clonic seizures, well controlled, not on anti epileptic medication for 6 years presented with frequent complex partial seizures, disorientation and deteriorating short term memory. EEG was normal however,
P M E Slade, C Lawthom
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This case demonstrates two uncommon conditions presenting in a single patient. A 47-year-old male with a history since childhood of generalised tonic clonic seizures, well controlled, not on anti epileptic medication for 6 years presented with frequent complex partial seizures, disorientation and deteriorating short term memory. EEG was normal however,
P M E Slade, C Lawthom
openaire +2 more sources