Results 31 to 40 of about 550,568 (326)

A comparison between internal protein nanoenvironments of α-helices and β-sheets.

open access: yesPLoS ONE, 2020
Secondary structure elements are generally found in almost all protein structures revealed so far. In general, there are more β-sheets than α helices found inside the protein structures.
Ivan Mazoni   +4 more
doaj   +1 more source

Um paradigma da química medicinal: a flexibilidade dos ligantes e receptores A medicinal chemistry paradigm: ligands and receptor flexibility

open access: yesQuímica Nova, 2005
In general, molecular modeling techniques applied in medicinal chemistry have been static and drug based. However the active site geometry and the intrinsic flexibility of both receptor and ligand are fundamental properties for molecular recognition and ...
Hugo Verli, Eliezer J. Barreiro
doaj   +1 more source

Multi-Photon Quantum Key Distribution Based on Double-Lock Encryption

open access: yes, 2015
This paper presents a multi-stage, multi-photon quantum key distribution protocol based on the double-lock cryptography. It exploits the asymmetry in the detection strategies between the legitimate users and the eavesdropper. The security analysis of the
Gottesman   +6 more
core   +1 more source

Experimentally realizable quantum comparison of coherent states and its applications [PDF]

open access: yes, 2006
When comparing quantum states to each other, it is possible to obtain an unambiguous answer, indicating that the states are definitely different, already after a single measurement. In this paper we investigate comparison of coherent states, which is the
B. Schneier   +11 more
core   +2 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Locks Fit into Keys: A Crystal Analysis of Lock Polynomials [PDF]

open access: yesAnnals of Combinatorics, 2020
21 pages, 10 figures, comments welcome!
openaire   +3 more sources

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

From Lock Freedom to Progress Using Session Types [PDF]

open access: yes, 2013
Inspired by Kobayashi's type system for lock freedom, we define a behavioral type system for ensuring progress in a language of binary sessions. The key idea is to annotate actions in session types with priorities representing the urgency with which such
Padovani, Luca
core   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

“Lock ‘Em Up . . .” but Where’s the Key? Transformative Drama with Incarcerated Youth

open access: yesJournal of Contemporary Issues in Education, 2014
A research study doing applied theatre with youth at an Alberta, Canada young offender facility, asks: How can participatory drama contribute to the education of incarcerated youth to avoid future negative outcomes of their “at-risk” behaviours?
Diane Conrad
doaj   +1 more source

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