Results 41 to 50 of about 597,682 (300)

“Lock ‘Em Up . . .” but Where’s the Key? Transformative Drama with Incarcerated Youth

open access: yesJournal of Contemporary Issues in Education, 2014
A research study doing applied theatre with youth at an Alberta, Canada young offender facility, asks: How can participatory drama contribute to the education of incarcerated youth to avoid future negative outcomes of their “at-risk” behaviours?
Diane Conrad
doaj   +1 more source

A comparison between internal protein nanoenvironments of α-helices and β-sheets.

open access: yesPLoS ONE, 2020
Secondary structure elements are generally found in almost all protein structures revealed so far. In general, there are more β-sheets than α helices found inside the protein structures.
Ivan Mazoni   +4 more
doaj   +1 more source

Locks Fit into Keys: A Crystal Analysis of Lock Polynomials [PDF]

open access: yesAnnals of Combinatorics, 2020
21 pages, 10 figures, comments welcome!
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Colloids with key-lock interactions: non-exponential relaxation, aging and anomalous diffusion

open access: yes, 2007
The dynamics of particles interacting by key-lock binding of attached biomolecules are studied theoretically. Experimental realizations of such systems include colloids grafted with complementary single-stranded DNA (ssDNA), and particles grafted with ...
Alexei V. Tkachenko   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ship Lock Extraction from High-Resolution Remote Sensing Images Based on Fuzzy Theory and Prior Knowledge

open access: yesRemote Sensing
As crucial water conservancy projects, ship locks play a key role in flood control, shipping, water resource allocation, and promoting regional economic development, making them an indispensable part of the modern water transportation system.
Bingsun Chen   +9 more
doaj   +1 more source

Theoretical Aspects of Molecular Recognition [PDF]

open access: yes, 2009
Molecular recognition is a key process in non-covalent interactions, which determines, among others, host-guest complexation, drug action and protein-protein interaction. A simple and attractive formulation is the lock-and-key analogy defining the host
Harmat, Veronika, Náray-Szabó, Gábor
core   +1 more source

Quantum-classical correspondence in circularly polarized high harmonic generation [PDF]

open access: yes, 2013
Using numerical simulations, we show that atomic high order harmonic generation, HHG, with a circularly polarized laser field offers an ideal framework for quantum-classical correspondence in strong field physics.
Bandrauk, A. D.   +4 more
core   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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