Results 31 to 40 of about 597,682 (300)
Química Nova, 2005 In general, molecular modeling techniques applied in medicinal chemistry have been static and drug based. However the active site geometry and the intrinsic flexibility of both receptor and ligand are fundamental properties for molecular recognition and ...
Hugo Verli, Eliezer J. Barreiro
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Non-destructive lock-picking of a historical treasure chest by means of X-ray computed tomography.
PLoS ONE, 2020 An innovative approach to a non-destructive lock mechanism examination by means of X-ray computed tomography (CT) was involved in a careful opening of a locked 19th century chest missing the key, as an interdisciplinary cooperation with the restorers. In
Eva Zikmundová +3 more
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DeepKey: Towards End-to-End Physical Key Replication From a Single Photograph [PDF]
, 2018 This paper describes DeepKey, an end-to-end deep neural architecture capable of taking a digital RGB image of an 'everyday' scene containing a pin tumbler key (e.g.
Alex Krizhevsky +4 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
A Fuel‐Driven Lock‐and‐Key System
ChemistryOpenThis study introduces a fuel‐driven lock‐and‐key system based on the interaction between crown ether and ammonium ion. In this simple model system, a key‐like molecule with an amino group functions as the key, while 15‐crown‐5 serves as the lock.
Shilin Zhang +4 more
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Smart Molecular Recognition: From Key-to-Lock Principle to Memory-Based Selectivity
Frontiers in Chemistry, 2020 The formation and decomposition of inclusion compounds with a solid-solid phase transition may be very selective to the guest molecular structure. This selectivity may function in essentially different ways than defined by the classical concept of ...
Askar K. Gatiatulin +2 more
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Energy-efficient and high-performance lock speculation hardware for embedded multicore systems [PDF]
, 2015 Embedded systems are becoming increasingly common in everyday life and like their general-purpose counterparts, they have shifted towards shared memory multicore architectures.
Bahar, R Iris +4 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
General Design Layout of Datengxia Ship Lock
Renmin Zhujiang, 2022 The Datengxia hydro project is a key project to open the 100-million-ton golden waterway of the Xijiang River,with high navigation requirements for the dam-site reach and a huge freight volume.The general design layout of the navigation structure ship ...
LI Yawen, CHEN Guihua
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source