Results 61 to 70 of about 597,682 (300)
The Lock-free $k$-LSM Relaxed Priority Queue
, 2015 Priority queues are data structures which store keys in an ordered fashion to allow efficient access to the minimal (maximal) key. Priority queues are essential for many applications, e.g., Dijkstra's single-source shortest path algorithm, branch-and ...
Gruber, Jakob +3 more
core +2 more sources
Robust quantum data locking from phase modulation [PDF]
, 2014 Quantum data locking is a unique quantum phenomenon that allows a relatively short key to (un)lock an arbitrarily long message encoded in a quantum state, in such a way that an eavesdropper who measures the state but does not know the key has essentially
Lloyd, Seth, Lupo, Cosmo, Wilde, Mark M.
core +3 more sources
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Beyond the fuzzy lock-and-key: spontaneous symmetry shifts and glycan/lectin logic gates [PDF]
, 2012 Changes in the molecular topology of glycan/lectin interaction may explain observed reaction punctuation driven by experimental gradients in reactant concentration. Adoption of a 'biological renormalization' perspective from statistical physics
Rodrick Wallace
core +1 more source
Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations [PDF]
, 2019 Receptor-ligand interactions are essential for biological function and their binding strength is commonly explained in terms of static lock-and-key models based on molecular complementarity.
Gonzalez, Laura +4 more
core +4 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Simple key locks turbine rotor blades [PDF]
, 1966 Symmetrical, cruciform key has end tabs which bend up to lock tubine rotor blades against axial displacement.
core +1 more source
Molecular Docking: From Lock and Key to Combination Lock
Journal of Molecular Medicine and Clinical Applications, 2018 Accurate modeling of protein ligand binding is an important step in structure-based drug design, is a useful starting point for finding new lead compounds or drug candidates. The 'Lock and Key' concept of protein-ligand binding has dominated descriptions of these interactions, and has been effectively translated to computational molecular docking ...
Ashutosh, Tripathi, Vytas A, Bankaitis
openaire +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Jurnal Ilmiah Informatika, 2016 Most of Safes lock system is still using conventional methods nowadays. The conventional method leads to the safes’ burglary. Some of the causes are the safes’ code that can be tracked easily and the key can be duplicated.
Muhammad Rofiq, Bambang Tri Wahjo Utomo
doaj +1 more source