Results 61 to 70 of about 74,015 (266)

Supporting energy technology deployment while avoiding unintended technological lock-in: a policy design perspective

open access: yesEnvironmental Research Letters, 2018
Technology deployment policies can play a key role in bringing early-stage energy technologies to the market and reducing their cost along their learning curves.
Leonore Haelg   +2 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

The Lock is the Key: Development of Novel Drugs through Receptor Based Combinatorial Chemistry

open access: yesActa Chimica Slovenica, 2017
Modern drug discovery is mainly based on the de novo synthesis of a large number of compounds with a diversity of chemical functionalities. Though the introduction of combinatorial chemistry enabled the preparation of large libraries of compounds from so-
Goran Šinko, Nikola Maraković
doaj   +1 more source

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi   +7 more
wiley   +1 more source

Exploring Topsnut-Graphical Passwords by Twin Odd-elegant Trees

open access: yesMATEC Web of Conferences, 2017
Graphical passwords are facing a good opportunity as 2-dimension codes are accepted by many people, since it has been applied in mobile devices, electronic equipments with touch screen, and so on.
Wang Hong-yu, Xu Jin, Yao Bing
doaj   +1 more source

Design of an Open-Source Decoder for Educational Escape Rooms

open access: yesIEEE Access, 2019
Escape rooms are a popular recreational activity which involves solving a series of puzzles within a time limit to `escape' the fictional setting they are in. As a fun, collaborative learning activity, escape rooms are increasingly finding their way into
Robert Ross
doaj   +1 more source

The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. [PDF]

open access: yesElife, 2021
Plassart L   +12 more
europepmc   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

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