Results 81 to 90 of about 6,638,555 (335)

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

The Extravagance of Imprisonment Revisited [PDF]

, 2010
This report analyzes prison and jail populations in the US as a whole and in four key states -- California, Florida, New York, and Texas -- to determine 1) how many prisoners are nonserious offenders and what it costs to lock them up, 2) what proven ...
Barry A. Krisberg, Christopher Hartney, Linh Vuong, Susan Marchionna   +3 more
core  

Lessons from Love-Locks: The archaeology of a contemporary assemblage [PDF]

, 2017
This document is the Accepted Manuscript version. The final, definitive version of this paper has been published in Journal of Material Culture, November 2017, published by SAGE Publishing, All rights reserved.Loss of context is a challenge, if not the ...
Bord J, Bradley R, Brück J, Ceri Houlbrook, Day JW, Douglas M, Dowden K, Fontijn DR, Gell A, Gruner E, Hammond CI, Houlbrook C, Houlbrook C, Jones A, Kalshoven PT, Laing LR, Lavrinec J, Leins I, Leins I, MacDowall L, Maiwald K, Mason R, Merrifield R, Miller D, Pietrobruno S, Priest V, Richards C, Score V, Score V, Stead IM, Thompson M, Williams J   +31 more
core   +2 more sources

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Research on Draft Control Optimization of Ship Passing a Lock Based on CFD Method

Journal of Marine Science and Engineering
Waterborne transportation serves as a critical pillar of trunk-line freight systems, offering unparalleled advantages in transport capacity, energy efficiency, and cost-effectiveness. As cargo throughput demands escalate, optimizing lock capacity becomes
Yuan Zhuang, Yu Ding, Jialun Liu, Song Zhang   +3 more
doaj   +1 more source

Uncovering noisy social signals: Using optimization methods from experimental physics to study social phenomena. [PDF]

PLoS ONE, 2017
Due to the ubiquitous presence of treatment heterogeneity, measurement error, and contextual confounders, numerous social phenomena are hard to study. Precise control of treatment variables and possible confounders is often key to the success of studies ...
Maurits Kaptein, Robin van Emden, Davide Iannuzzi   +2 more
doaj   +1 more source

Two-beam nonlinear Kerr effect to stabilize laser frequency with sub-Doppler resolution

, 2012
Avoiding laser frequency drifts is a key issue in many atomic physics experiments. Several techniques have been developed to lock the laser frequency using sub-Doppler dispersive atomic lineshapes as error signals in a feedback loop.
Ackemann, Baluschev, Banerjee, Bjorkholm, Gea-Banacloche, Harris, Lett, Petelski, Rovera, Yoshikawa   +9 more
core   +1 more source

Experimentally realizable quantum comparison of coherent states and its applications [PDF]

, 2006
When comparing quantum states to each other, it is possible to obtain an unambiguous answer, indicating that the states are definitely different, already after a single measurement. In this paper we investigate comparison of coherent states, which is the
B. Schneier, D. Achilles, Erika Andersson, H. Barnum, I. Jex, Igor Jex, K. Mattle, Marcos Curty, P. Törmä, P. W. Shor, R. Loudon, W. Diffie   +11 more
core   +2 more sources

Accuracy of diagnostic codes and algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in administrative claims and electronic health records: systematic review and meta‐analysis.

Arthritis Care &Research, Accepted Article.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in electronic health records (EHRs). Methods We searched MEDLINE, Embase, and CENTRAL databases and included studies that validated case definitions against a reference standard such ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Key Generation for Hardware Obfuscation Using Strong PUFs

Cryptography, 2019
As a result of the increased use of contract foundries, intellectual property (IP) theft, excess production and reverse engineering are major concerns for the electronics and defense industries.
Md Shahed Enamul Quadir, John A. Chandy   +1 more
doaj   +1 more source