Results 41 to 50 of about 1,614,631 (234)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Security for 5G Mobile Wireless Networks

open access: yesIEEE Access, 2018
The advanced features of 5G mobile wireless network systems yield new security requirements and challenges. This paper presents a comprehensive study on the security of 5G wireless network systems compared with the traditional cellular networks.
Dongfeng Fang, Yi Qian, Rose Qingyang Hu
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Novel key management and authentication scheme for ad hoc space networks

open access: yesTongxin xuebao, 2006
To be implemented using a flexible distributed architecture consisting of a constellation of dynamically de-ployed or configured satellites that were networked together into an integrated information system,the satellites could form an ad hoc self ...
YANG De-ming, MU De-jun, XU Zhong
doaj  

Secure Session Key Management Scheme for Meter-Reading System Based on LoRa Technology

open access: yesIEEE Access, 2018
Long range (LoRa) technology is a wireless communication technology, which may provide low-power, low-rate, and LoRa communication. It may widely be used into many applications, such as smart metering and factory monitoring.
Zhuoqun Xia   +5 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Survey of wireless sensor network security techniques

open access: yesTongxin xuebao, 2007
The current situations of sensor network security,the security challenges and the security problems were pre-sented.From the aspects of key management,secure routing,authentication,intrusion detection,DoS attack,access con-trol,all the security ...
PEI Qing-qi1   +2 more
doaj  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Research on large-scale identity authentication architecture based on combined symmetric key

open access: yesTongxin xuebao, 2009
A large-scale real-name authentication architecture and key management protocol based on combined symmet-ric key algorithm were proposed.With the CSK algorithm and smart card technology, the authentication process can be finished in the chips, and the ...
LIU Tong, XU Guan-ning
doaj  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

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