Results 51 to 60 of about 1,614,631 (234)

Domain-based key management for heterogeneous wireless sensor networks

open access: yesTongxin xuebao, 2009
Key management was one of the most challenging security problems in wireless sensor networks. Based on the random key pre-distribution scheme, a new scheme was proposed for heterogeneous wireless sensor networks using deployment knowledge of the node and
MA Chun-guang   +2 more
doaj  

Key Management Systems at the Cloud Scale

open access: yesCryptography, 2019
This paper describes a cloud-scale encryption system. It discusses the constraints that shaped the design of Amazon Web Services’ Key Management Service, and in particular, the challenges that arise from using a standard mode of operation such as ...
Matthew Campagna, Shay Gueron
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

VERIFICATION OF KEY MANAGEMENT CRYPTOGRAPHIC PROTOCOLS WITH COLORED PETRI NETS

open access: yesВестник Донского государственного технического университета, 2018
The possibility of using colored Petri nets for the analysis of key distribution cryptographic protocols as an example of symmetric Needham—Schroeder protocol is reviewed and evaluated.
Nadezhda S. Mogilevskaya   +1 more
doaj  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Survey of key management schemes for cluster networks

open access: yes网络与信息安全学报, 2022
With the rapid development of artificial intelligence and communication network technology, increasing attention has been paid to cluster intelligence.Cluster network is an important part of cluster intelligence, the security of information interaction ...
Jun LIU, Lin YUAN, Zhishang FENG
doaj  

A Lightweight and Flexible Encryption Scheme to Protect Sensitive Data in Smart Building Scenarios

open access: yesIEEE Access, 2018
Smart buildings represent key environments to encourage the growth of more sustainable and efficient cities. With the strong development of the Internet of Things (IoT), the integration of heterogeneous physical devices fosters the emergence of data ...
Salvador Perez   +6 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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