Results 71 to 80 of about 1,614,631 (234)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Butterfly Encryption Scheme for Resource-Constrained Wireless Networks

open access: yesSensors, 2015
Resource-constrained wireless networks are emerging networks such as Radio Frequency Identification (RFID) and Wireless Body Area Networks (WBAN) that might have restrictions on the available resources and the computations that can be performed.
Raghav V. Sampangi, Srinivas Sampalli
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Cryptographic Protection in Maintenance and Management System of Ground Vehicles

open access: yesБезопасность информационных технологий, 2012
This article is devoted to the implementation of the cryptographic protection of messages passed between the on-board terminals (BT) and control centers (CC) in maintenance and management system of ground vehicles.
M. M. Gruntovich, A. N. Syomkin
doaj  

Attack Algorithm for a Keystore-Based Secret Key Generation Method

open access: yesEntropy, 2019
A new attack algorithm is proposed for a secure key generation and management method introduced by Yang and Wu. It was previously claimed that the key generation method of Yang and Wu using a keystore seed was information-theoretically secure and could ...
Seungjae Chae   +3 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

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