Results 81 to 90 of about 1,483,664 (290)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A Lightweight and Flexible Encryption Scheme to Protect Sensitive Data in Smart Building Scenarios

open access: yesIEEE Access, 2018
Smart buildings represent key environments to encourage the growth of more sustainable and efficient cities. With the strong development of the Internet of Things (IoT), the integration of heterogeneous physical devices fosters the emergence of data ...
Salvador Perez   +6 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

A Hybrid Key Pre-Distribution Scheme for Securing Communications in Wireless Sensor Networks

open access: yesJOIV: International Journal on Informatics Visualization, 2019
Wireless Sensor Network (WSN) is a type of ad hoc networks which consist of hundreds to thousands of sensor nodes. These sensor nodes collaborate to surveillance environment.
Mojtaba Jamshidi   +3 more
doaj   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Cryptographic Protection in Maintenance and Management System of Ground Vehicles

open access: yesБезопасность информационных технологий, 2012
This article is devoted to the implementation of the cryptographic protection of messages passed between the on-board terminals (BT) and control centers (CC) in maintenance and management system of ground vehicles.
M. M. Gruntovich, A. N. Syomkin
doaj  

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