Results 41 to 50 of about 54,307 (258)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

WSN key recovery attack based on symmetric matrix decomposition

Tongxin xuebao, 2018
The key protocol is one of the crucial technologies to ensure the security for wireless sensor network（WSN）.Parakh,et al.proposed a key agreement for WSN based on matrix decomposition.However,the study revealed that the protocol had security risks.A key ...
Xiangmin JI, Bo ZHAO, Jinhui LIU, Jianwei JIA, Huanguo ZHANG, Shuang XIANG   +5 more
doaj   +2 more sources

Security Analysis of Conditional Privacy-Preserving Authentication Schemes for VANETs

IEEE Access, 2023
In order to solve security and privacy-preservation issues in VANETs, a number of conditional privacy-preservation schemes based on certificateless signature (CLS) schemes and certificateless aggregate signature (CLAS) schemes have been proposed. However,
Kyung-Ah Shim
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Walsh Spectrum Puncturing Revisited: Toward Automated Linear Key Recovery Attacks

IACR Transactions on Symmetric Cryptology
Linear cryptanalysis has long served as a cornerstone in the security analysis of symmetric-key cryptanalytic primitives. Through more than 30 years of community efforts, it has become routine to use automated tools to search for the optimal linear ...
Chengan Hou, Shuyi Wang, Meicheng Liu
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Improved integral cryptanalysis of block cipher Zodiac

Cybersecurity
Integral cryptanalysis is a pivotal technique in symmetric-key cryptography. This paper enhances the integral key-recovery analysis of the Feistel-based cipher Zodiac by introducing a systematic framework for identifying optimal key recovery attack paths.
Yi Guo, Danping Shi, Lei Hu, Xu Guo, Zhiru Chen   +4 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Analyzing the Probability of Key Recovery in the Differential Attacks Against ChaCha

IEEE Access
The stream cipher ChaCha has been subjected to differential linear cryptanalysis since 2008. Aumasson et al. (2008) laid the groundwork for this attack, employing the concept of probabilistically neutral bits for key recovery.
Nitin Kumar Sharma, Sabyasachi Dey
doaj   +1 more source