Results 71 to 80 of about 181,059 (277)
Science ProgressReciprocating piston pump is an important power equipment in coal mine production, so the research on condition monitoring and fault diagnosis of reciprocating piston pump is of great significance.
Yuehua Lai +3 more
doaj +1 more source
Intersection Homology. General perversities and topological invariance
, 2019 Topological invariance of the intersection homology of a pseudomanifold without codimension one strata, proven by Goresky and MacPherson, is one of the main features of this homology. This property is true for codimension-dependent perversities with some
Chataur, David +2 more
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Energies, 2018 Understanding how mining-induced strata movement, fractures, bed separation, and ground subsidence evolve is an area of great importance for the underground coal mining industry, particularly for disaster control and sustainable mining.
Weibing Zhu, Shengchao Yu, Jingmin Xu
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Meitan kexue jishuAt present, longwall top coal caving (LTCC) mining is main mining method for safety and efficiency mines with extremely-thick coal seam in China. However, the deformation movement law of overlying strata on LTCC face directly affects rock pressure ...
Xinxian ZHAI +4 more
doaj +1 more source
Advances in Civil Engineering, 2021 In recent years, in order to increase the coal recovery rate, the large mining height fully mechanized top-coal caving mining has been widely used because it has the advantages of both fully mechanized mining method and large mining height mining method.
Baisheng Zhang +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source