Results 31 to 40 of about 1,603 (131)

Investigation of autonomic nervous system functions by pupillometry in children with Attention-Deficit/Hyperactivity Disorder

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: Attention deficit hyperactivity disorder (ADHD) is one of the most frequently seen neurodevelopmental disorders among schoolaged children.
Koray Kara   +5 more
doaj   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

open access: yesAdvanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan   +13 more
wiley   +1 more source

Anticonvulsant property of celecoxib in maximal electroshock seizure: Correlating the role of inflammation in pathophysiology of epileptic seizures

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Epilepsy is an abnormal excessive electric neuronal activity and always represents by recurrent seizures. There is positive feedback cycle between epileptogenesis and brain inflammation.
Raina Jain, Neeraj Khare, Ashish Jain
doaj   +1 more source

CD14 plays a critical role in pain and inflammation across multiple models of post‐traumatic osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine OA models that vary in severity of pathology and rate of progression, to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt   +18 more
wiley   +1 more source

«The ucommunist program» in the context of the KGB secret case «Block» realization

open access: yesНауковий вісник Чернівецького національного університету імені Юрія Федьковича. Історія, 2019
The article analyzes the course and results of the KGB investigation of the identification of the author of the self-published document «The Ukommunist Program» in the framework of the case of block operative development “Block” in 1972.
Bohdan Paska
doaj   +1 more source

Dietitian‐led very low‐calorie diet for preoperative rehabilitation in patients with obesity awaiting non‐bariatric elective laparoscopic surgery: A retrospective study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Obesity increases the risks and complexity of laparoscopic surgeries. Preoperative very low‐calorie diets (VLCDs) can demonstrate significant preoperative weight loss. However, the optimal VLCD duration remains unclear. Excessive loss of muscle mass associated with VLCDs may elevate surgical and postoperative risks. This study aimed
Gerald Wei Shen Wong   +4 more
wiley   +1 more source

The day of civil resistance: KGB reaction to events in 1972

open access: yesGenocidas ir Rezistencija, 2003
At the beginning of 1972, in comparison to other cities, Kaunas did not stand out in terms of the number of people persecuted or followed by the KGB, or in terms of any illegal movement.
Arvydas Anušauskas
doaj   +1 more source

Evolutionary Dynamic Multiobjective Optimisation Assisted by Inverse Regression Tree Predictor

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Dynamic multiobjective optimisation problems (DMOPs) are optimisation problems with multiple conflicting objectives that can change over time. Most dynamic multiobjective optimisation evolutionary algorithms (DMOEAs) attempt to estimate Pareto‐optimal sets (PS) directly in the decision space.
Kai Gao, Lihong Xu
wiley   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

Functional Data Strengthen Clinical Validation of PhenoScore Phenotype‐Guided AI for ANKRD11 Missense Variants

open access: yesClinical Genetics, EarlyView.
PhenoScore, an AI framework integrating facial recognition and clinical phenotype data, accurately identifies pathogenic ANKRD11 missense variants associated with KBG syndrome (AUC 0.95). Validated against functional data, PhenoScore outperforms REVEL and complements AlphaMissense, providing objective phenotypic evidence to reduce variants of uncertain
Evi Andriessen   +5 more
wiley   +1 more source

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