Results 11 to 20 of about 23,936 (270)

Khat-induced conditioned place preference, extinction, and reinstatement in female mice [PDF]

IBRO Neuroscience Reports
Khat (Catha edulis Forsk), the natural source of cathinone and other psychoactive agents, is chewed by millions of persons in eastern Africa and the Arabian Peninsula for its psychostimulant effect.
Caroline K. Murithi, Jacques M. Kabaru, Nilesh B. Patel   +2 more
doaj   +2 more sources

Coenzyme Q10 nullified khat-induced hepatotoxicity, nephrotoxicity and inflammation in a mouse model

Heliyon, 2020
Ethnopharmacological relevance: The consumption of khat (Catha Edulis, Forsk) is on the rise despite the much publicized associated deleterious health effects. How chemicals present in khat, affect various physiological and biochemical processes requires
Chepukosi Kennedy, Patrick Okanya, James Nyabuga Nyariki, Peris Amwayi, Ngalla Jillani, Alfred Orina Isaac   +5 more
doaj   +1 more source

Effect of Regular Khat Chewing on Serum Fasting Sugar Level in Diabetic patients versus Healthy Individuals; A comparative study

Nutrition and Metabolic Insights, 2021
Background: Khat chewing is a long standing social-cultural habit in several countries. Even though many people chew khat simply for its pleasurable and stimulatory effect, evidence showed widely-held belief among khat chewers in Ethiopia and other part ...
Yordanos Mengistu, Gobena Dedefo, Mesay Arkew, Gebeyehu Asefa, Gutema Jebessa, Abay Atnafu, Zerihun Ataro, Samuel Kinde   +7 more
doaj   +1 more source

Influence of co-administration of Khat (Catha edulis Forsk) and metformin on metabolic syndrome in high fructose diet induced type 2 diabetes in rats

National Journal of Physiology, Pharmacy and Pharmacology, 2021
Background: Despite numerous reports regarding the associations of Khat chewing with serious health adverse effects, a significant number of people worldwide uses Khat daily, especially in its origin countries.
Nabil Ahmed Albaser, Abdel-Wahab H Mohamad, Mohammed Amood Al-Kamarany   +2 more
doaj   +1 more source

Khat induced psychotic disorder: case report

Substance Abuse Treatment, Prevention, and Policy, 2020
Background Khat (Catha edulis) is a stimulant leaf khat comes from a tree which grows in countries bordering the Red Sea which are along the east coast of Africa and in west Asia. The psycho- active component within these leaves is cathinone. In Ethiopia,
Elias Tesfaye, Wolfgang Krahl, Selamawit Alemayehu   +2 more
doaj   +1 more source

Evaluation of the cytotoxic and genotoxic potential of Khat (Catha edulis Forsk) extracts on human T lymphoblastoid cell line [PDF]

, 2004
This paper reports on an investigation of the cytotoxic and genotoxic potential of khat extract using a human T lymphoblastoid cell line (CEM). Exponentially growing CEM cells were cultured for 12 h in the presence of khat extract (0-2000 μg ml-1 ...
Al-Meshal, Al-Meshal, Barnett, C.N. Fokunang ., C.R. Barnett ., Fenech, Gunaid, Hammouda, Kabarity, Kalix, Kamel, Morton, O’Gara, O’Gara, P.T. Tomkins ., Reed, S.S. Barkwan, Sakagam, Sharma, Y.A. Barnett ., Zheng   +20 more
core   +1 more source

Acute khat use reduces response conflict in habitual users

Frontiers in Human Neuroscience, 2013
Khat consumption has become a worldwide phenomenon broadening from Eastern Africa and the south west of the Arabian Peninsula to ethnic communities in the rest of the world.
Lorenza S Colzato, Roberta eSellaro, Manuel eRuiz, Manuel eRuiz, Katarzyna eSikora, Bernhard eHommel   +5 more
doaj   +1 more source

Regulating khat - Dilemmas and opportunities for the international drug control system [PDF]

, 2009
Background: The regulation of khat, one of the most recent psychoactive drugs to become a globally traded commodity, remains hotly contested within different producer and consumer countries.
Beckerleg, Susan, Hailu, D. (Degol), Klein, A. (Axel)   +2 more
core   +1 more source

Seven in every ten khat chewers in Gondar City had an intention to stop khat chewing: cross-sectional study using Transtheoretical Model

BMC Psychiatry, 2020
Background Khat chewing practice is rapidly expanding worldwide and currently, an estimated over 10 million people chew khat daily. The transtheoretical model explains how behavior change occurs across the stages of change.
Asmamaw Adugna, Telake Azale, Simegnew Handebo   +2 more
doaj   +1 more source

Herbal highs: review on psychoactive effects and neuropharmacology [PDF]

, 2017
Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S, Orsolini, L, Pichini, S., Rotolo, Mc, Schifano, F, Tittarelli, R   +5 more
core   +1 more source