Results 1 to 10 of about 179 (114)

Antiplasmodial, Antioxidant and Cytotoxicity Activity of Ethanol and Aqueous Extracts of Khaya grandifoliola Stem Bark [PDF]

Journal of Tropical Medicine, 2023
Background. Malaria is a serious public health problem, especially in sub-Saharan Africa. The aim of this study was to scientifically provide baseline information on the use of Khaya grandifoliola stem bark as an antimalaria drug by traditional healers ...
Gamago Nkadeu Guy-Armand, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Mounvera Abdel Azizi, Ngouyamsa Nsapkain Aboubakar Sidiki, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne   +7 more
doaj   +4 more sources

Inhibitory activity of limonoids from Khaya grandifoliola C.DC (Meliaceae) against hepatitis C virus infection in vitro [PDF]

Avicenna Journal of Phytomedicine, 2021
Objective: A fraction from Khaya grandifoliola has recently been shown to inhibit hepatitis C virus (HCV) infection and three limonoids (17-epi-methyl-6-hydroxylangolensate, 7-deacetoxy-7-oxogedunin and 7-deacetoxy-7R-hydroxygedunin) were purified from ...
Kouam Arnaud, Njayou Frédéric Nico, Yuan Fei, Babayemi Oladejo, He Hongtao, Mkounga Pierre, Moundipa Paul   +6 more
doaj   +4 more sources

Comparative study of physico-chemical properties of some molecules from Khaya Grandifoliola plant [PDF]

Scientific Reports
The three molecular compounds: A (17-epi-methyl-6-hydroxylangolensate), B (7-deacetoxy-7-oxogedunin) and C (7-deacetoxy-7R-hydroxygedunin) isolated from Khaya Grandifoliola, a plant of the Meliaceae family, able to protect the normal human hepatocyte ...
E. R. Atangana Nkene, R. A. Yossa Kamsi, H. Zangue Adjia, M. T. Ottou Abe, A. Teyou Ngoupo, J. M. B. Ndjaka   +5 more
doaj   +4 more sources

Efficacy of Khaya grandifoliola Stem Bark Ethanol Extract in the Treatment of Cerebral Malaria in Swiss albino Mice Using Plasmodium berghei NK65 Strain [PDF]

Journal of Parasitology Research, 2023
Background. Cerebral malaria is one of the most severe and dangerous forms of malaria and is potentially fatal. This study was aimed at evaluating the anticerebral malaria efficacy of Khaya grandifoliola used by traditional healers. Method.
Gamago Nkadeu Guy-Armand, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Tako Djimefo Alex Kevin, Tientcheu Noutong Jemimah Sandra, Ngouyamsa Nsapkain Aboubakar Sidiki, Mounvera Abdel Azizi, Vincent Khan Payne   +7 more
doaj   +2 more sources

Linn and C.DC. Reduce Oxidative Stress and Ameliorate -Induced Parasitemia and Cytokines in BALB/c Mice [PDF]

Journal of Evidence-Based Integrative Medicine, 2021
Background. Annona muricata and Khaya grandifoliola are ethnomedicinally used for the treatment of malaria and have been experimentally shown to have an anti-plasmodial effect, but the mechanisms involved are not fully understood. This study investigated
Hope Onohuean MSc, PhD Fellow, Abdullateef I. Alagbonsi PhD, Ibe M. Usman MSc, PhD Fellow, Keneth Iceland Kasozi MSc, PhD Fellow, Athanasios Alexiou PhD, Reem H. Badr PhD, Gaber El-Saber Batiha PhD, Joseph O. C. Ezeonwumelu MSc, PhD Fellow   +7 more
doaj   +2 more sources

Hydro-ethanolic extract of Khaya grandifoliola attenuates heavy metals-induced hepato-renal injury in rats by reducing oxidative stress and metals-bioaccumulation [PDF]

Heliyon, 2022
People living in developing countries are exposed to hepato-renal injuries induced by heavy metals like lead (Pb), cadmium (Cd), and mercury (Hg) since drinking water supplied is often polluted with a high concentration of those metals.
Arnaud Fondjo Kouam, Micheline Masso, Ferdinand Elombo Kouoh, Rodrigue Fifen, Ibrahim Njingou, Angèle Nkouatchoua Tchana, Frédéric Nico Njayou, Paul Fewou Moundipa   +7 more
doaj   +2 more sources

Morfobiometria de frutos, sementes e plântulas de Khaya grandifoliola

Pesquisa Florestal Brasileira, 2023
 Objetivou-se neste trabalho realizar a caracterização morfobiométrica de frutos, sementes e plântulas de Khaya grandifoliola. Os frutos foram caracterizados pela avaliação do comprimento, diâmetro e espessura do pericarpo, e as sementes pelo ...
Marcos Lopes de Campos, Andréia Márcia Santos de Souza David, Deyvisson Rodrigues Pinto, Ruthelly Viereca Sena Rocha, Franson Ronner Pereira Alves, Josiane Cantuária Figueiredo, Eliene Almeida Paraizo   +6 more
doaj   +2 more sources

Genetic diversity in populations of African mahogany (Khaya grandioliola C. DC.) introduced in Brazil [PDF]

Genetics and Molecular Biology, 2020
Given its high-valued wood, the African mahogany (Khaya grandifoliola) has been envisaged as a renewable source of tropical hardwoods in Brazil. However, there are concerns about the hypothesized low diversity among the few K.
Sabrina Delgado Soares, Ludmila Ferreira Bandeira, Stela Barros Ribeiro, Mariana Pires de Campos Telles, João Augusto da Silva, Canrobert Tormin Borges, Alexandre Siqueira Guedes Coelho, Evandro Novaes   +7 more
doaj   +3 more sources

Inhibition of lipopolysaccharide (LPS)-induced neuroinflammatory response by polysaccharide fractions of Khaya grandifoliola (C.D.C.) stem bark, Cryptolepis sanguinolenta (Lindl.) Schltr and Cymbopogon citratus Stapf leaves in raw 264.7 macrophages and U87 glioblastoma cells [PDF]

BMC Complementary and Alternative Medicine, 2018
Background Khaya grandifoliola (C.D.C.) stem bark, Cymbopogon citratus (Stapf) and Cryptolepis sanguinolenta (Lindl.) Schltr leaves are used in Cameroonian traditional medicine for the treatment of inflammatory diseases.
Francine Kengne Mediesse, Thaddée Boudjeko, Anantharaju Hasitha, Matharasala Gangadhar, Wilfred Fon Mbacham, Perumal Yogeeswari   +5 more
doaj   +2 more sources

Genetic resources of African mahogany in Brazil: genomic diversity and structure of forest plantations [PDF]

BMC Plant Biology
Background African mahogany species (Khaya sp.) have been introduced to Brazil gaining increasing economic interest over the last years, as they produce high quality wood for industrial applications.
Júlio Cézar Tannure Faria, Enéas Ricardo Konzen, Marcos Vinicius Winckler Caldeira, Tiago de Oliveira Godinho, Luciana Prata Maluf, Sarah Ola Moreira, Carolina da Silva Carvalho, Bárbara Simões Santos Leal, Cássia dos Santos Azevedo, Dione Richer Momolli, Gracielle Teodora da Costa Pinto Coelho, Conceição de Maria Batista de Oliveira, Taís Cristina Bastos Soares   +12 more
doaj   +2 more sources