Results 1 to 10 of about 3,205 (166)

Inhibitory activity of limonoids from Khaya grandifoliola C.DC (Meliaceae) against hepatitis C virus infection in vitro [PDF]

Avicenna Journal of Phytomedicine, 2021
Objective: A fraction from Khaya grandifoliola has recently been shown to inhibit hepatitis C virus (HCV) infection and three limonoids (17-epi-methyl-6-hydroxylangolensate, 7-deacetoxy-7-oxogedunin and 7-deacetoxy-7R-hydroxygedunin) were purified from ...
Kouam Arnaud, Njayou Frédéric Nico, Yuan Fei, Babayemi Oladejo, He Hongtao, Mkounga Pierre, Moundipa Paul   +6 more
doaj   +7 more sources

Antiplasmodial, Antioxidant and Cytotoxicity Activity of Ethanol and Aqueous Extracts of Khaya grandifoliola Stem Bark [PDF]

Journal of Tropical Medicine, 2023
Background. Malaria is a serious public health problem, especially in sub-Saharan Africa. The aim of this study was to scientifically provide baseline information on the use of Khaya grandifoliola stem bark as an antimalaria drug by traditional healers ...
Gamago Nkadeu Guy-Armand, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Mounvera Abdel Azizi, Ngouyamsa Nsapkain Aboubakar Sidiki, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne   +7 more
doaj   +5 more sources

Comparative study of physico-chemical properties of some molecules from Khaya Grandifoliola plant [PDF]

Scientific Reports
The three molecular compounds: A (17-epi-methyl-6-hydroxylangolensate), B (7-deacetoxy-7-oxogedunin) and C (7-deacetoxy-7R-hydroxygedunin) isolated from Khaya Grandifoliola, a plant of the Meliaceae family, able to protect the normal human hepatocyte ...
E. R. Atangana Nkene, R. A. Yossa Kamsi, H. Zangue Adjia, M. T. Ottou Abe, A. Teyou Ngoupo, J. M. B. Ndjaka   +5 more
doaj   +5 more sources

Biometric assessment of early stem growth at a commercial stand of African mahogany (Khaya grandifoliola) [PDF]

Bioscience Journal, 2023
African mahogany species (Khaya spp.) have proven to be promising in the Brazilian forestry scenario, replacing native mahogany owing to their medium-fast growth and relevant timber value. This study aimed to carry out forest inventory and assessments of
Renan Krupok Matias, Camilla Nascimento Brito, Rafael Tassinari Resende, Jovan Martins Rios, Gabriel Mendes Santana, Guilherme Murilo de Oliveira, Fábio Venturoli   +6 more
doaj   +5 more sources

Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity [PDF]

Frontiers in Pharmacology, 2017
Drug-induced liver injury (DILI) is a major clinical problem where natural compounds hold promise for its abrogation. Khaya grandifoliola (Meliaceae) is used in Cameroonian traditional medicine for the treatment of liver related diseases and has been ...
Arnaud F. Kouam, Arnaud F. Kouam, Fei Yuan, Frédéric N. Njayou, Hongtao He, Roméo F. Tsayem, Babayemi O. Oladejo, Fuhang Song, Paul F. Moundipa, George F. Gao   +9 more
doaj   +6 more sources

Efficacy of Khaya grandifoliola Stem Bark Ethanol Extract in the Treatment of Cerebral Malaria in Swiss albino Mice Using Plasmodium berghei NK65 Strain [PDF]

Journal of Parasitology Research, 2023
Background. Cerebral malaria is one of the most severe and dangerous forms of malaria and is potentially fatal. This study was aimed at evaluating the anticerebral malaria efficacy of Khaya grandifoliola used by traditional healers. Method.
Gamago Nkadeu Guy-Armand, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Tako Djimefo Alex Kevin, Tientcheu Noutong Jemimah Sandra, Ngouyamsa Nsapkain Aboubakar Sidiki, Mounvera Abdel Azizi, Vincent Khan Payne   +7 more
doaj   +3 more sources

Linn and C.DC. Reduce Oxidative Stress and Ameliorate -Induced Parasitemia and Cytokines in BALB/c Mice [PDF]

Journal of Evidence-Based Integrative Medicine, 2021
Background. Annona muricata and Khaya grandifoliola are ethnomedicinally used for the treatment of malaria and have been experimentally shown to have an anti-plasmodial effect, but the mechanisms involved are not fully understood. This study investigated
Hope Onohuean MSc, PhD Fellow, Abdullateef I. Alagbonsi PhD, Ibe M. Usman MSc, PhD Fellow, Keneth Iceland Kasozi MSc, PhD Fellow, Athanasios Alexiou PhD, Reem H. Badr PhD, Gaber El-Saber Batiha PhD, Joseph O. C. Ezeonwumelu MSc, PhD Fellow   +7 more
doaj   +3 more sources

Hydro-ethanolic extract of Khaya grandifoliola attenuates heavy metals-induced hepato-renal injury in rats by reducing oxidative stress and metals-bioaccumulation [PDF]

Heliyon, 2022
People living in developing countries are exposed to hepato-renal injuries induced by heavy metals like lead (Pb), cadmium (Cd), and mercury (Hg) since drinking water supplied is often polluted with a high concentration of those metals.
Arnaud Fondjo Kouam, Micheline Masso, Ferdinand Elombo Kouoh, Rodrigue Fifen, Ibrahim Njingou, Angèle Nkouatchoua Tchana, Frédéric Nico Njayou, Paul Fewou Moundipa   +7 more
doaj   +3 more sources

Anthelmintic Activity of Ethanolic and Aqueous Extracts of Khaya grandifoliola Stem Bark against Heligmosomoides polygyrus: In Vitro and In Silico Approaches [PDF]

Journal of Tropical Medicine
Background. Parasitic infection remains a serious health trade for humans and livestock. The purpose of this study was to present scientific proof of the anthelmintic properties of Khaya grandifoliola, which the native population uses to cure ...
Noumedem Anangmo Christelle Nadia, Mahdi Yaghoobi, Yamssi Cédric, Masoud Besati, Yungong Misparine Kiki, Ngouyamsa Nsapkain Aboubakar Sidiki, Mounvera Abdel Azizi, Vincent Khan Payne, Haibo Hu   +8 more
doaj   +3 more sources

Wood density of forest species in integrated crop-livestock-forest system in the Brazilian Amazon: challenges and opportunities for Bertholletia excelsa, Dipteryx odorata, and Khaya grandifoliola [PDF]

Revista Brasileira de Ciências Ambientais
Wood density is the physical property directly related to the timber potential of a species and influences the environmental service of carbon storage and sequestration. Therefore, the objective of this study was to evaluate the wood density at different
Lizandra Elizeário dos Santos, Carlos Tadeu dos Santos Dias, Emanuel José Gomes de Araújo, Aureane Cristina Teixeira Ferreira Cândido, Paulo Campos Christo Fernandes, Arystides Resende Silva, Afonso Henrique Moraes Oliveira, Victor Hugo Pereira Moutinho, Lucieta Guerreiro Martorano   +8 more
doaj   +4 more sources