Anthelmintic Activity of Ethanolic and Aqueous Extracts of Khaya grandifoliola Stem Bark against Heligmosomoides polygyrus: In Vitro and In Silico Approaches [PDF]
Background. Parasitic infection remains a serious health trade for humans and livestock. The purpose of this study was to present scientific proof of the anthelmintic properties of Khaya grandifoliola, which the native population uses to cure ...
Noumedem Anangmo Christelle Nadia +8 more
doaj +3 more sources
Exploring the Anthelmintic, Antioxidant, and Cytotoxic Potential of Khaya grandifoliola and Faidherbia albida Extract Combinations: In Vitro Studies on Heligmosomoides polygyrus and Caenorhabditis elegans [PDF]
Background Soil‐transmitted helminth infection is endemic in Chad and constitutes a public health problem, particularly among school‐age children. The aim of this study was to evaluate the synergistic anthelmintic activity of the combined extracts of Khaya grandifoliola and Faidherbia albida used in Chad by traditional practitioners for the treatment ...
Yamssi Cédric +6 more
doaj +3 more sources
Hypsipyla robusta Moore (Lepidoptera: Pyralidae), like many other moth species, shows selectivity when choosing host plants for its eggs. Four Meliaceae species (Khaya grandifoliola, K.
C. B. Darko +4 more
doaj +2 more sources
Antimalarial Activity of Khaya Grandifoliola Stem-bark [PDF]
Khaya grandifoliola (Welw) CDC (Meliaceae) is widely used in West Africa for the treatment of fever. The dried powdered stem-bark of the plant was extracted with various solvents. The resulting extracts and column purified fractions therefrom were tested for their antimalarial properties using Plasmodium berghei berghei for in vivo antimalarial ...
J.M. Agbedahunsi +3 more
exaly +2 more sources
Genetic resources of African mahogany in Brazil: genomic diversity and structure of forest plantations [PDF]
Background African mahogany species (Khaya sp.) have been introduced to Brazil gaining increasing economic interest over the last years, as they produce high quality wood for industrial applications.
Júlio Cézar Tannure Faria +12 more
doaj +2 more sources
Delayed treatment with hydro-ethanolic extract of Khaya grandifoliola protects mice from acetaminophen-hepatotoxicity through inhibition of c-Jun N-terminal kinase phosphorylation and mitochondrial dysfunction [PDF]
The use of N-acetylcysteine against acetaminophen(APAP)-induced hepatotoxicity, a leading cause of liver injury, has several drawbacks, including short therapeutic windows.
Arnaud Fondjo Kouam +7 more
doaj +2 more sources
African mahogany species (Khaya spp.) have proven to be promising in the Brazilian forestry scenario, replacing native mahogany owing to their medium-fast growth and relevant timber value. This study aimed to carry out forest inventory and assessments of
Renan Krupok Matias +6 more
doaj +2 more sources
Leveraging target enrichment and genome skimming (Hyb-Seq) of herbarium collections to unlock timber DNA barcoding. [PDF]
Abstract Premise DNA barcoding for timber species identification requires comprehensive reference datasets, informative DNA barcodes, and cost‐effective protocols. We developed a workflow leveraging Hyb‐Seq (target capture sequencing and genome skimming) to address these challenges, and we tested it on four genera from the mahogany family (Meliaceae ...
Bellot S +14 more
europepmc +2 more sources
Neuroinflammation is a common hallmark of Alzheimer's disease (AD), with NLRP3 inflammasome proven to be activated in microglia of AD patients' brains. In this study, a newly isolated biflavonoid (7,7'-di-O-methylchamaejasmin/M8) and a crude extract of the plant Khaya grandifoliola (KG) were investigated for their inhibitory effect on inflammasome ...
Brice Ayissi Owona +2 more
exaly +5 more sources

