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Antiplasmodial, Antioxidant and Cytotoxicity Activity of Ethanol and Aqueous Extracts of Khaya grandifoliola Stem Bark [PDF]

open access: yesJournal of Tropical Medicine, 2023
Background. Malaria is a serious public health problem, especially in sub-Saharan Africa. The aim of this study was to scientifically provide baseline information on the use of Khaya grandifoliola stem bark as an antimalaria drug by traditional healers ...
Gamago Nkadeu Guy-Armand   +7 more
doaj   +5 more sources

Inhibitory activity of limonoids from Khaya grandifoliola C.DC (Meliaceae) against hepatitis C virus infection in vitro [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2021
Objective: A fraction from Khaya grandifoliola has recently been shown to inhibit hepatitis C virus (HCV) infection and three limonoids (17-epi-methyl-6-hydroxylangolensate, 7-deacetoxy-7-oxogedunin and 7-deacetoxy-7R-hydroxygedunin) were purified from ...
Kouam Arnaud   +6 more
doaj   +6 more sources

Efficacy of Khaya grandifoliola Stem Bark Ethanol Extract in the Treatment of Cerebral Malaria in Swiss albino Mice Using Plasmodium berghei NK65 Strain [PDF]

open access: yesJournal of Parasitology Research, 2023
Background. Cerebral malaria is one of the most severe and dangerous forms of malaria and is potentially fatal. This study was aimed at evaluating the anticerebral malaria efficacy of Khaya grandifoliola used by traditional healers. Method.
Gamago Nkadeu Guy-Armand   +7 more
doaj   +3 more sources

Sustainability of Mahogany Production in Plantations: Does Resource Availability Influence Susceptibility of Young Mahogany Plantation Stands to Hypsipyla robusta Infestation? [PDF]

open access: yesInternational Journal of Forestry Research, 2022
Hypsipyla robusta Moore (Lepidoptera: Pyralidae), like many other moth species, shows selectivity when choosing host plants for its eggs. Four Meliaceae species (Khaya grandifoliola, K.
C. B. Darko   +4 more
doaj   +4 more sources

Hydro-ethanolic extract of Khaya grandifoliola attenuates heavy metals-induced hepato-renal injury in rats by reducing oxidative stress and metals-bioaccumulation [PDF]

open access: yesHeliyon, 2022
People living in developing countries are exposed to hepato-renal injuries induced by heavy metals like lead (Pb), cadmium (Cd), and mercury (Hg) since drinking water supplied is often polluted with a high concentration of those metals.
Arnaud Fondjo Kouam   +1 more
exaly   +4 more sources

Comparative study of physico-chemical properties of some molecules from Khaya Grandifoliola plant [PDF]

open access: yesScientific Reports
The three molecular compounds: A (17-epi-methyl-6-hydroxylangolensate), B (7-deacetoxy-7-oxogedunin) and C (7-deacetoxy-7R-hydroxygedunin) isolated from Khaya Grandifoliola, a plant of the Meliaceae family, able to protect the normal human hepatocyte ...
E. R. Atangana Nkene   +5 more
doaj   +4 more sources

Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity [PDF]

open access: yesFrontiers in Pharmacology, 2017
Drug-induced liver injury (DILI) is a major clinical problem where natural compounds hold promise for its abrogation. Khaya grandifoliola (Meliaceae) is used in Cameroonian traditional medicine for the treatment of liver related diseases and has been ...
Fei Yuan   +2 more
exaly   +4 more sources

Biometric assessment of early stem growth at a commercial stand of African mahogany (Khaya grandifoliola) [PDF]

open access: yesBioscience Journal, 2023
African mahogany species (Khaya spp.) have proven to be promising in the Brazilian forestry scenario, replacing native mahogany owing to their medium-fast growth and relevant timber value. This study aimed to carry out forest inventory and assessments of
Renan Krupok Matias   +6 more
doaj   +4 more sources

Linn and C.DC. Reduce Oxidative Stress and Ameliorate -Induced Parasitemia and Cytokines in BALB/c Mice [PDF]

open access: yesJournal of Evidence-Based Integrative Medicine, 2021
Background. Annona muricata and Khaya grandifoliola are ethnomedicinally used for the treatment of malaria and have been experimentally shown to have an anti-plasmodial effect, but the mechanisms involved are not fully understood. This study investigated
Hope Onohuean MSc, PhD Fellow   +7 more
doaj   +2 more sources

Khayae (Meliaceae) specierum nomenclator [PDF]

open access: yes, 2017
Le présent article constitue une mise au point nomenclaturale du genre Khaya A. Juss., circonscrit à l'Afrique continentale, Madagascar et aux Comores. Ce genre contient un petit nombre de taxons, de quatre à six espèces selon les auteurs.
Dipelet Bouka, Gaël Ulrich   +3 more
core   +2 more sources

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