Results 211 to 220 of about 137,214 (262)

Ki‐1 (CD30) antigen is released by Ki‐1‐positive tumor cells in vitro and in vivo. I. Partial characterization of soluble Ki‐1 antigen and detection of the antigen in cell culture supernatants and in serum by an enzyme‐linked immunosorbent assay

European Journal of Immunology, 1989
AbstractAn enzyme‐linked immunosorbent assay (ELISA) has been developed that allows the quantitative determination of the Ki‐1 (CD30) antigen in soluble form. Similar levels of sensitivity of this new Ki‐1 ELISA and the ELISA previously described for measuring the soluble 55‐kDa chain of the interleukin 2 receptor were seen. As assessed with this ELISA,
O, Josimovic-Alasevic, H, Dürkop, R, Schwarting, E, Backé, H, Stein, T, Diamantstein   +5 more
openaire   +2 more sources

Acute Infectious Mononucleosis: CD30 (Ki-1) Antigen Expression and Histologic Correlations

American Journal of Clinical Pathology, 1990
Lymph nodes from patients with acute infectious mononucleosis (AIM) typically show marked paracortical expansion and a prominent immunoblastic proliferation that can occur in nodules and sheets, as well as within sinuses. The marked immunoblastic proliferation, coupled with Reed-Sternberg-like cells and a polymorphous inflammatory cell background, may ...
S L, Abbondanzo, N, Sato, S E, Straus, E S, Jaffe   +3 more
openaire   +2 more sources

Genotypic analysis of large cell lymphomas which express the Ki‐1 antigen

Histopathology, 1987
The monoclonal antibody Ki‐1 reacts with Reed‐Sternberg cells in Hodgkin's disease and with the tumour cells in a minority of large cell non‐Hodgkin's lymphomas. This study describes the results of immunophenotypic and DNA analysis in 30 cases of non‐Hodgkin's lymphoma, all of which expressed the Ki‐1 antigen. The genotypic analysis has been undertaken
N T, O'Connor, H, Stein, K C, Gatter, J S, Wainscoat, J, Crick, T, Al Saati, B, Falini, G, Delsol, D Y, Mason   +8 more
openaire   +2 more sources

The Hodgkin-Associated Ki-1 Antigen Exists in an Intracellular and a Membrane-Bound Form

Biological Chemistry Hoppe-Seyler, 1989
The Hodgkin-associated Ki-1 antigen occurs in two different molecular forms. The 120-kDa membrane-associated form is a phosphorylated glycoprotein, which is derived from a non-phosphorylated intracellular 84-kDa apoprotein that is co-translationally N-glycosylated with a carbohydrate portion of 6 kDa.
H, Hansen, H, Lemke, G, Bredfeldt, I, Könnecke, B, Havsteen   +4 more
openaire   +2 more sources

Cultured human NK cells express the Ki-1/CD30 antigen.

British journal of haematology, 1993
In this study we show that in vitro cultured human polyclonal NK cell lines and clones express the Ki-1/CD30 Hodgkin-associated antigen, identified by the BER-H2 monoclonal antibody. The percentage of BER-H2+ cells ranged from 19% to 67% in five polyclonal NK cell lines and was 31% and 20% in two NK clones.
Cambiaggi A, CANTONI, CLAUDIA, Marciano S, De Totero D, Pileri S, Tazzari PL, Stein H, Ferrini S.   +7 more
openaire   +2 more sources

Protein kinase activity of the intracellular but not of the membrane-associated form of the KI-1 antigen (CD30)

Research in Immunology, 1990
The Hodgkin-associated Ki-1 antigen (CD30) consists of a 120-kDa membrane-associated glycosylated phosphoprotein (Ki-1/120) and a 57-kDa non-glycosylated phosphoprotein (Ki-1/57) which only occurs intracellularly. Both molecules are phosphorylated at serine residues.
H, Hansen, G, Bredfeldt, B, Havsteen, H, Lemke   +3 more
openaire   +2 more sources

Interleukn‐2 Receptor Antigen, Leukocyte Common Antigen, and Ki‐1 Antigen‐expressing Gastric Plasmacytoma A Case Report with an Immunohistochemical Study

Acta Pathologica Japonica, 1990
A case of primary gastric plasmacytoma expressing various surface and cytoplasmic antigens is reported. With the use of formalin‐fixed and deparaffinized sections, 13 different antibodies were applied. Neoplastic plasma cells revealed monoclonal IgG and x light chain in the cytoplasm, and expressed epithelial membrane antigen, Ki 67 antigen ...
T, Ohmori, N, Uraga, K, Komi, R, Tabei, R, Matsuda, T, Kodama, K, Iwahashi   +6 more
openaire   +2 more sources

Expression of a Hodgkin and Reed-Sternberg cell associated antigen (Ki-1) in cutaneous lymphoid infiltrates

Archives of Dermatological Research, 1987
Skin biopsy specimens from normal skin and from 115 patients with benign dermatoses, pre- or pseudo-malignant disorders or malignant cutaneous lymphomas have been examined immunohistologically for expression of the Reed-Sternberg cell associated antigen CD30 detected by monoclonal antibodies Ki-1 and Ber-H2. The antibodies stained the atypical cells in
E, Ralfkiaer, J, Bosq, K C, Gatter, R, Schwarting, J, Gerdes, H, Stein, D Y, Mason   +6 more
openaire   +2 more sources

Potential application and prevalence of the CD30 (Ki-1) antigen among solid tumors: A focus review of the literature

Critical Reviews in Oncology/Hematology, 2017
CD30 (Ki-1) is a cell membrane protein derived from the tumor necrosis factor (TNF) receptor family. The CD30 antigen has been associated primarily with Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (sALCL). Brentuximab vedotin (BV) is an antibody-drug conjugate targeting the CD30 antigen.
Garrett K, Berger, Kevin, Gee, Cassandra, Votruba, Ali, McBride, Faiz, Anwer   +4 more
openaire   +2 more sources