Results 151 to 160 of about 1,145,786 (286)
Advanced Science, EarlyView.Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki +7 more
wiley +1 more source
ANALISIS EKSPRESI Cdk6 DAN Ki-67 PADA NEOPLASMA KELENJAR LIUR [PDF]
, 2016 Background: Tumors with broad spectrum can arise in salivary glands and giving diagnostic difficulties in some subtypes due to morphologic similarities. Immunohistocemistry studies done to differentiate between benign and malignant neoplasms of salivary ...
Meyta Riniastuti, NIM011181409
core
Advanced Science, EarlyView.We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
Prediction of Ki-67 Expression in HIV-Associated Lung Adenocarcinoma Patients Using Multiple Machine Learning Models Based on CT Imaging Radiomics [PDF]
Chang Song,1,* Jingsong Chen,2,* Chunyan Zhao,1,* Shulin Song,3,* Tong Yang,4 Aichun Huang,1 Renhao Liu,1 Yanxi Pan,3 Chaoyan Xu,1 Canling Chen,1 Qingdong Zhu1 1Tuberculosis Department, Nanning Fourth People’s Hospital, Nanning, Guangxi ...
Pan Y +10 more
core +1 more source
Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
Advanced Science, EarlyView.This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source
Advanced Science, EarlyView.Interlayer sliding in the RuO2Zn2F2 bilayer induces ferroelectricity and enables reversible valley polarization switching. The electric dipole and valley‐resolved band edges are intimately coupled, revealing sliding ferroelectricity as a powerful mechanism for electrical control of valley degrees of freedom in 2D materials.
Djamel Bezzerga +3 more
wiley +1 more source
Ki-67 som prognostisk markør for prostatakreft. Betydningen av proliferasjonsraten til prostatakreftceller målt ved bruk av Ki-67 [PDF]
, 2016 Metode: Det ble laget vevsmatriser (TMA, tissue micro array) fra 535 pasienter med prostatakreft. Fra forhåndsmarkerte områder med epitelialt tumorvev, stromalt tumorvev, normale epitelceller og normale stromale celler ble det stanset ut vev for å lage ...
Movik, Ingeborg Marie
core
Advanced Science, EarlyView.A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo +13 more
wiley +1 more source
Advanced Science, EarlyView.Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral +7 more
wiley +1 more source