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Noninvasive Prediction of High Ki-67 Expression in Hepatocellular Carcinoma Using Multiparametric MRI and Clinical Biomarkers. [PDF]
J Hepatocell CarcinomaZhang F +8 more
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Combined Ki-67 and feulgen stain for morphometric determination of the Ki-67 labelling index
Histochemistry, 1993In this note we present a combined Ki-67 and Feulgen stain for morphometric determination of the Ki-67 labelling index. The immunohistochemical part of this double staining technique is based on the alkaline-phosphatase-anti-alkaline-phosphatase (APAAP) method, visualizing the enzyme activity by the nitro-blue-tetrazolium chloride (NBT)/bromo-chloro-3 ...
H, Kolles +3 more
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Ki-67 Expression in Vulvar Carcinoma
International Journal of Gynecological Pathology, 1994The proliferative activity of invasive squamous cell carcinoma of the vulva was examined using a Ki-67 equivalent monoclonal antibody (MIB1), which gives a strong immunoreaction in paraffin-embedded tissue. Quantitation of Ki-67 immunostaining was accomplished by image analysis. Ki-67 immunostaining revealed two general patterns of reactivity in vulvar
J B, Hendricks +5 more
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Neurosurgery, 2009
KI-67, A MARKER of cellular proliferation, has been studied extensively in pituitary neoplasia. It is of relevance to various clinicopathological parameters, including tumor subtype, size, invasiveness, and recurrence, as well as patient age and sex. Generally, pituitary tumors behaving aggressively have increased Ki-67 labeling indices.
Fateme, Salehi +5 more
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KI-67, A MARKER of cellular proliferation, has been studied extensively in pituitary neoplasia. It is of relevance to various clinicopathological parameters, including tumor subtype, size, invasiveness, and recurrence, as well as patient age and sex. Generally, pituitary tumors behaving aggressively have increased Ki-67 labeling indices.
Fateme, Salehi +5 more
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Oral Oncology, 2010
To analyze the prognostic value of Ki-67 in oral cancer and its relationship with Ki-67 expression in precancerous epithelium.We studied 79 tumors from 65 patients. Immunohistochemistry study with Mib-1 monoclonal antibody was used to detect Ki-67 expression in tumor tissue and adjacent non-tumor tissue. The influence of different variables on survival
M A, Gonzalez-Moles +4 more
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To analyze the prognostic value of Ki-67 in oral cancer and its relationship with Ki-67 expression in precancerous epithelium.We studied 79 tumors from 65 patients. Immunohistochemistry study with Mib-1 monoclonal antibody was used to detect Ki-67 expression in tumor tissue and adjacent non-tumor tissue. The influence of different variables on survival
M A, Gonzalez-Moles +4 more
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Ki-67 – new faces of an old player
Orvosi Hetilap, 2009Huszonöt évvel ezelőtt izolálták először a Ki-67 fehérjét, ami napjainkra az osztódó sejtek első számú hisztológiai markere lett. Ez a kivételes szerkezetű molekula olyan alapvető biológiai funkciókkal bír, amelyek nélkülözhetetlenek a normális sejtciklushoz.
Tamás, Bubán +4 more
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Ki‐67 and p53 in T2 laryngeal cancer
The Laryngoscope, 1998AbstractObjective: To study the relationship between the proliferative capacity, represented by the immunohistochemical labeling index (LI) of proliferation marker Ki‐67, and the p53 status, as in theory an intact p53 cell cycle checkpoint system should result in a lower proliferative capacity.
A, Kropveld +4 more
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Ki-67 is an indicator of progression of neuroendocrine tumors
Endocrine Pathology, 1994No current histological or cytological indices can distinguish reliably malignant from benign tumors in neuroendocrine tumors, including pheochromocytomas, pancreatic endocrine tumors, and carcinoid tumors. We investigated immunohistochemically the expression of Ki-67 in 52 neuroendocrine tumors, including 17 pheochromocytomas, 9 pancreatic endocrine ...
Noriko, Kimura +5 more
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The Ki-67 protein: From the known and the unknown
Journal of Cellular Physiology, 2000The expression of the human Ki-67 protein is strictly associated with cell proliferation. During interphase, the antigen can be exclusively detected within the nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes.
T, Scholzen, J, Gerdes
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Ki-67 Labeling Index in Breast Cancer
Tumori Journal, 1989Measurements of cell cycle kinetics have been found to correlate with the clinical course of patients with breast cancer. However, the thymidine labeling index and more rapid methods like flow cytometry remain complicated and costly. We assessed cell proliferation of 67 breast carcinomas by an immunoperoxidase procedure using a monoclonal antibody, Ki ...
S, Crispino +9 more
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