Results 131 to 140 of about 94,068 (259)

α2,3‐Sialyltransferase (ST3Gal1) regulates endometrioid‐type epithelial ovarian cancer cell migration and invasion via VEGF‐R2/JAK2/STAT3 signaling cascades

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao, Chia‐Hao Liu, Szu‐Ting Yang, Chen‐Hao Lin, Liang‐Wei Wang, Peng‐Hui Wang   +5 more
wiley   +1 more source

Ki-67 as a treatment decision modifier in breast cancer. [PDF]

Oncologist
Dy A, Lennerz JK.
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Colonic Perineurioma Presenting as a Small Subepithelial Lesion With Distinctive Endoscopic Findings. [PDF]

DEN Open
Takedomi H, Shirozu M, Fukuda K, Yao T, Esaki M.   +4 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Characterizing immune heterogeneity in gastric cancer by high-throughput T-cell receptor sequencing: predictive clonotypes and functional signatures. [PDF]

Transl Cancer Res
Liu T, Chen Z, Cheng G, Xu L, Gan L, Ye Z, Shen X.   +6 more
europepmc   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

iRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li, Aiyan Ji, Qihang Ding, Hongyue Lou, Zhen Cheng   +4 more
wiley   +1 more source

Evaluation of the Proliferation Marker Ki-67 for Improved Risk Stratification of Prostate Cancer Patients Under Active Surveillance. [PDF]

Diagnostics (Basel)
Schütz V, Rothermel M, Kaczorowski A, Dieffenbacher S, Böning SH, Schwab C, Stenzinger A, Huber J, Duensing A, Hohenfellner M, Duensing S.   +10 more
europepmc   +1 more source

Epirubicin Alters Pancreatic Autophagy and Insulin Synthesis Through a Zinc‐Dependent Mechanism

Journal of Applied Toxicology, EarlyView.
ABSTRACT Epirubicin (EPI) can cause metabolic side effects, including chemotherapy‐related diabetes, partly through oxidative stress that disrupts zinc (Zn) homeostasis and impairs autophagy. This study investigated the effects of EPI on Zn regulation and autophagy in the pancreas, as well as the modulatory role of N‐acetylcysteine (NAC). Rats received
Ebru Afşar, Işıl Eranıl
wiley   +1 more source

Expression of Estrogen Receptor Alpha and Ki-67 in Synchronous Canine Mammary Tumors. [PDF]

J Mammary Gland Biol Neoplasia
Hansen N, Moberg IM, Solbakken MH, Gunnes G, Borge KS, Arnet EF, Guttersrud OA, Bergholtz H, Lingaas F.   +8 more
europepmc   +1 more source