Results 61 to 70 of about 155,758 (281)

Correlation of fluorodeoxyglucose uptake and tumor-proliferating antigen Ki-67 in lymphomas

Journal of Cancer Research and Therapeutics, 2012
To investigate the correlation between cellular proliferation and the fluorodeoxyglucose (FDG) uptake in positron emission tomography/computed tomography (PET/CT) imaging by comparing 50 cases of different subtypes of lymphoma.Fifty cases of lymphomas were collected.
Yi, Shou, Jianping, Lu, Tao, Chen, Dalie, Ma, Linjun, Tong   +4 more
openaire   +2 more sources

Heterogeneity of proliferative markers in pancreatic β-cells of patients with severe hypoglycemia following Roux-en-Y gastric bypass. [PDF]

, 2017
Severe postprandial hypoglycemia with neuroglycopenia is an increasingly recognized, debilitating complication of Roux-en-Y gastric bypass (RYGB) surgery.
Folli, F., Goldfine, A.B., Goldsmith, J., Hoem, D., Hu, J., Kulkarni, R.N., La Rosa, S., Molven, A., Patti, M.E., Schwesinger, W.H.   +9 more
core   +2 more sources

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Data on clinical significance of GAS2 in colorectal cancer cells

Data in Brief, 2016
The growth arrest-specific 2 (GAS2) was cloned and found to be upregulated in the feces of recurrent CRC patients. This overexpressed GAS2 induced different patterns of gene expressions in CRC cells. Briefly, one cell proliferation marker, Ki-67 antigen (
Chun-Chao Chang, Chi-Cheng Huang, Shung-Haur Yang, Chih-Cheng Chien, Chia-Long Lee, Chi-Jung Huang   +5 more
doaj   +1 more source

Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo. [PDF]

, 2009
BackgroundProstate stem/progenitor cells function in glandular development and maintenance. They may be targets for tumor initiation, so characterization of these cells may have therapeutic implications.
Garraway, Isla P, Goldstein, Andrew S, Hahm, Scott A, Haider, Maahum, Head, Christian S, Perner, Sven, Reiter, Robert E, Rubin, Mark A, Sun, Wenyi, Tran, Chau P, Witte, Owen N, Zhang, Bao   +11 more
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Prognostic significance of DNA cytometry in cutaneous malignant lymphomas. [PDF]

, 1991
The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome.
Abmayr, Wolfgang, Braun-Falco, Otto, Burg, Günter, Dummer, Reinhard, Eckert, Fritjof, Kaudewitz, Peter, Stolz, Wilhelm, Vogt, Thomas   +7 more
core   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Epitope analysis of antibodies recognising the cell proliferation associated nuclear antigen previously defined by the antibody Ki-67 (Ki-67 protein). [PDF]

Journal of Clinical Pathology, 1994
AIMS--To elucidate the fine specificities of the antibodies MIB 1 and MIB 3 and of additional monoclonal antibodies which also recognise the Ki-67 protein (MIB 5, IND.64, JG-67-2a). METHODS--Different parts of the Ki-67 protein cDNA were expressed in Escherichia coli.
M H, Kubbutat, G, Key, M, Duchrow, C, Schlüter, H D, Flad, J, Gerdes   +5 more
openaire   +2 more sources

TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection. [PDF]

, 2016
HIV infection induces phenotypic and functional changes to CD8+ T cells defined by the coordinated upregulation of a series of negative checkpoint receptors that eventually result in T cell exhaustion and failure to control viral replication.
Abdel-Mohsen, Mohamed, Burwitz, Benjamin J, Chew, Glen M, Clayton, Kiera L, Deeks, Steven G, Fujita, Tsuyoshi, Hammond, Katherine B, Hansen, Scott G, Hecht, Frederick M, Ishii, Naoto, Korman, Alan J, Liegler, Teri, Maurer, Mark, Mitchell, Brooks I, Ndhlovu, Lishomwa C, Ostrowski, Mario, Reed, Jason S, Sacha, Jonah B, Shikuma, Cecilia M, Webb, Gabriela M, Wu, Helen L   +20 more
core   +3 more sources