Results 61 to 70 of about 94,380 (259)
Influence of phototherapy in psoriasis on ki-67 antigen expression: a preliminary study
Polish Journal of Pathology, 2013 Antigen Ki-67 is a non-histone nuclear protein, closely connected with cell proliferation. Determining Ki-67 allows for a quick and reliable evaluation of the growth fraction of the studied cell population. It serves as a marker of proliferative activity in neoplasms and other diseases with excessive cell proliferation such as psoriasis.<br /> ...
D, Jesionek-Kupnicka +2 more
openaire +2 more sources
Advanced Science, EarlyView.This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai +12 more
wiley +1 more source
Expression of Progestrone Receptor and Proliferative Marker ki 67, in Various Grades of Meningioma [PDF]
Acta Medica Iranica, 2010 Meningiomas are slow-growing neoplasms which recur locally, their morphologic grading is simple but do not always correlate with patient outcome. The aim of present study is to evaluate the status of progesterone receptor (PR) and proliferation marker ...
Nasrin Shayanfar +2 more
doaj +2 more sources
Journal of Research in Medical Sciences, 2019 Background: Breast cancer is the most common diagnosed female cancer. Breast cancer is also the leading cause of cancer death in females accounting for 13.7% of female cancer-related mortality globally.
Hosein Kamranzadeh +6 more
doaj +1 more source
Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor
Advanced Science, EarlyView.The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao +11 more
wiley +1 more source
FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model
Advanced Science, EarlyView.FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble +9 more
wiley +1 more source
In Response to "Intratumor Distribution of Ki-67 Antigen Beyond Labeling Index for Clinical Decision Making: A New Way of Counting". [PDF]
JTO Clin Res Rep, 2021 Belderbos RA +2 more
europepmc +1 more source
Advanced Science, EarlyView.This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source
Immunohistochemical evaluation of p53 and Ki-67 proteins in colorectal adenomas
Arquivos de Gastroenterologia, 2012 CONTEXT: The appearance of adenomas and their progression to adenocarcinomas is the result of an accumulation of genetic changes in cells of the intestinal mucosa inherited or acquired during life.
Walysson Alves Tocantins de Sousa +3 more
doaj +1 more source
Intratumor Distribution of Ki-67 Antigen Beyond Labeling Index for Clinical Decision-Making: A New Way of Counting. [PDF]
JTO Clin Res Rep, 2021 Bulloni M, Pattini L, Pelosi G.
europepmc +1 more source