Results 21 to 30 of about 2,560,491 (267)

Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A

Neurobiology of Disease, 2008
The down-regulation of protein phosphatase 2A (PP2A) activity is thought to play an important role in the formation of tau hyperphosphorylation in the Alzheimer's disease (AD) brain. Methylation of the PP2A catalytic subunit at the L309 site can potently
Xin-Wen Zhou, Jan-Åke Gustafsson, Heikki Tanila, Cecilia Bjorkdahl, Rong Liu, Bengt Winblad, Jin-Jing Pei   +6 more
doaj   +1 more source

Results of an early second PCR test performed on SARS-CoV-2 positive patients may support risk assessment for severe COVID-19

Scientific Reports, 2021
Identifying patients at increased risk for severe COVID-19 is of high priority during the pandemic as it could affect clinical management and shape public health guidelines.
Barak Mizrahi, Maytal Bivas-Benita, Nir Kalkstein, Pinchas Akiva, Chen Yanover, Yoav Yehezkelli, Yoav Kessler, Sharon Hermoni Alon, Eitan Rubin, Gabriel Chodick   +9 more
doaj   +1 more source

Increased rates of unattained developmental milestones among Israeli children between 2016 and 2020: a national report

Israel Journal of Health Policy Research, 2023
Background The early years of children’s lives are critical for their healthy development. Although children’s growth and development rates may vary, a significant delay during early childhood could indicate a medical or a developmental disorder ...
Irena Girshovitz, Guy Amit, Inbal Goldshtein, Deena R. Zimmerman, Ravit Baruch, Pinchas Akiva, Meytal Avgil Tsadok, Yair Sadaka   +7 more
doaj   +1 more source

The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation. [PDF]

, 2016
Nucleolar protein interacting with the FHA domain of pKi-67 (NIFK) is a Ki-67-interacting protein. However, its precise function in cancer remains largely uninvestigated.
Chang, Hong-Tai, Chang, Yu-Chang, Chen, Chi-Long, Ger, Luo-Ping, Hsiao, Michael, Huang, Ming-Shyan, Jan, Yi-Hua, Lai, Tsung-Ching, Lin, Tsung-Chieh, Lin, Yuan-Feng, Liu, Yu-Peng, Pan, Wen-An, Shyy, John Y-J, Su, Chia-Yi, Tsai, Ming-Daw, Wu, Pei-Yu, Yang, Chih-Jen, Yeh, Chi-Tai   +17 more
core   +2 more sources

Dr. rer. oec. Katja Gehrke

Monitor Versorgungsforschung
Die Nutzung von Daten für die medizinische Versorgung ist ein Trend, der das Gesundheitssystem in den nächsten Jahren nachhaltig verändern wird. „Gesundheitsdaten befeuern das lernende Gesundheitssystem der Zukunft“ wurde bereits 2019 prognostiziert und ...
Dr. rer. oec. Katja Gehrke, Prof. Dr. phil. Andreas Meusch   +1 more
doaj   +1 more source

The time-dependent localization of Ki 67 antigen-positive cells in human skin wounds [PDF]

, 1993
A total of 77 human skin wounds with a post-infliction interval between 3 h and 7 months were investigated and the proliferation marker antigen Ki 67 was visualized in paraffin sections using a specific monoclonal antibody (MIB).
A. Nerlich, DC Brown, E Ralfkiaer, EA Hell, H Cottier, J Gerdes, J Gerdes, J-P Ortonne, J. T�bel, J. Wilske, JL Cordell, M Oehmichen, M Oehmichen, P Betz, P Betz, P Betz, P Block, P. Betz, R Ross, R. Penning, RMM McMinn, RV Vito De, W. Eisenmengen   +22 more
core   +1 more source

τBu₂SiF-Derivatized D₂-Receptor Ligands: The First SiFA-Containing Small Molecule Radiotracers for Target-Specific PET-Imaging [PDF]

, 2011
The synthesis, radiolabeling and in vitro evaluation of new silicon-fluoride acceptor (SiFA) derivatized D-2-receptor ligands is reported. The SiFA-technology simplifies the introduction of fluorine-18 into target specific biomolecules for Positron ...
Bartenstein, Peter, Höfner, Georg, Iovkova-Berends, Ljuba, Jurkschat, Klaus, Kostikov, Alexey, Rensch, Christian, Schirrmacher, Ralf, Wanner, Klaus Theodor, Wängler, Björn, Wängler, Carmen, Zöller, Thomas   +10 more
core   +2 more sources

Red supergiants as potential Type IIn supernova progenitors: Spatially resolved 4.6 micron CO emission around VY CMa and Betelgeuse

, 2008
We present high-resolution 4.6micron CO spectra of the circumstellar environments of two RSGs that are potential SN progenitors: Betelgeuse and VY CMa. Around Betelgeuse, 12CO emission within 3arcsec follows a mildly clumpy but otherwise spherical shell,
Bensammar, Buscher, Chevalier, Choi, Chugai, Chugai, Davies, de Jager, Gal-Yam, Gilliland, Gray, Gustafsson, Harper, Harper, Harper, Heger, Hinkle, Huggins, Humphreys, Humphreys, Humphreys, Humphreys, Humphreys, Jones, Justtanont, Kastner, Kenneth H. Hinkle, Le Sidaner, Lipscy, Lobel, Lobel, Loup ., Maeder, Massey, Mauron, Mauron, Mauron, Mauron, Mauron, Meynet, Monnier, Monnier, Monnier, Monnier, Montes, Muller, Nathan Smith, Nils Ryde, Pooley, Rinehart, Ryde, Ryde, Shinnaga, Skinner, Smith, Smith, Smith, Smith, Smith, Smith, Smith, Turatto, Ueta, Uitenbroek, Vink, Wallerstein, Williams, Wilson, Wilson, Wittkowski, Zheng, Zickgraf   +71 more
core   +1 more source

Potassium Iodide in Dermatology- Recent Advances in Mechanism of Action, Preparation, Uses and Adverse Effects

Indian Journal of Dermatology
Potassium iodide (KI) is a simple yet versatile drug. It has been successfully used for the treatment of various diseases in dermatology, but there are very limited studies on the exact mechanism of action, preparation, and dosage of potassium iodide ...
Nishant Goel, Bhavana R. Doshi
doaj   +1 more source

The comfort zone: Reflection on a taken-for-granted model [PDF]

, 2008
Reference to the comfort zone model is widespread within outdoor adventure education. It is based on the belief that when placed in a stressful situation people will respond by overcoming their hesitancy and grow.
Brown, Mike
core   +1 more source