Results 41 to 50 of about 2,560,491 (267)

On the use of crude eigenvalue bounds in the solution of robbin's problems [PDF]

open access: yes, 1973
In this paper we consider what effect the use of crude eigenvalue estimates, for the evaluation of the iterative parameters, has on the convergence of the A.D.I.
Iordandis, KI
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Solving Robbin's problem [PDF]

open access: yes, 1972
In this report the numerical integration of ellipticpartial differential equations under Robbin's boundaryconditions is attempted by means of the Extrapolatedform of the Alternating Direction Implicit methods.A set of varying extrapolation parameters is ...
Lordanidis, KI
core  

Effective theory of color superconductivity

open access: yes, 2007
We briefly review an effective theory of QCD at high baryon density, describing the relevant modes near the Fermi surface. The high density effective theory has properties of reparametrization invariance and gauge invariance, maintained in a subtle way ...
Hong, Deog Ki
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Role of vertex corrections in the $T$-linear resistivity at the Kondo breakdown quantum critical point

open access: yes, 2011
The Kondo breakdown scenario has been claimed to allow the $T$-linear resistivity in the vicinity of the Kondo breakdown quantum critical point, two cornerstones of which are the dynamical exponent $z = 3$ quantum criticality for hybridization ...
Kim, Ki-Seok
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

A NEW APPROACH TO DISINFECTION OF CLEANROOMS (MICROBIOLOGICALLY ASPECTS)

open access: yesРазработка и регистрация лекарственных средств, 2019
Microbiological studies conducted the effectiveness of surfaces decontamination by using potassium iodide submicron aerosol, made by the device Generator of sea air «Aeroiodine». We used bacteria of the genus Staphylococcus as the test cultures.
N. P. Sachivkina
doaj  

Relationships and implications for complementary and alternative medicine in Aotearoa New Zealand: A discussion paper [PDF]

open access: yes, 2019
The purpose of this paper is to initiate a discussion on contextualising the relationship between the nursing profession and complementary and alternative medicine (CAM) within Aotearoa New Zealand.
Te Huia, Maria
core  

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