Results 31 to 40 of about 715,372 (292)
Indian Journal of DermatologyPotassium iodide (KI) is a simple yet versatile drug. It has been successfully used for the treatment of various diseases in dermatology, but there are very limited studies on the exact mechanism of action, preparation, and dosage of potassium iodide ...
Nishant Goel, Bhavana R. Doshi
doaj +1 more source
, 2018 A: DAPI Image. B: Segmented Nuclei. C: Ki-67 staining image (CY5 Channel). D: Binarized Ki-67 Stain. E: Overlap of B and D, to identify Ki-67+ nuclei (white arrows) and Ki-67- nuclei (red arrows). Scale bars = 50 microns.
Inês Godet (6160553) +3 more
core +1 more source
Einsatz von KI mit Fokus Kundenkommunikation
, 2023 In der vorliegenden Studie werden die Einsatzmöglichkeiten von KI aus der Sicht von Anwenderunternehmen betrachtet. Die Studie basiert auf der qualitativen Auswertung von Experteninterviews mit Vertretern von KI-Dienstleistern.
Drawehn, Jens, Pohl, Verena
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Künstliche Intelligenz in der Literaturrecherche
BibliothekKünstliche Intelligenz sieht Muster, die dem Menschen verborgen bleiben, und die Beschäftigung damit fasziniert ihn. Der Artikel untersucht, in welchem Maß diese Mustererkennung auf die Literatursuche umgesetzt werden kann.
Walder Anton
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
smartCasaplus – ein risikobasiertes geriatrisches Gesundheitscoaching für multimorbide Versicherte
Monitor VersorgungsforschungDas geriatrische Schulungsprogramm Casaplus der MedicalContact AG bietet bereits seit 2007 telefonische Gesundheitscoachings für multimorbide geriatrische Versicherte, von dem bereits ca. 30.000 Versicherte profitiert haben.
Prof. Dr. rer. pol. Stephan Burger +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source