Results 41 to 50 of about 2,542,347 (220)

KI oder nicht KI?

open access: yesMedienimpulse
Generative künstliche Intelligenz (KI) ist in der Hochschulbildung angekommen und dient zunehmend der Nutzung im wissenschaftlichen Schreibprozess.
Karin Tengler, Gerhard Brandhofer
doaj   +1 more source

Solving Robbin's problem [PDF]

open access: yes, 1972
In this report the numerical integration of ellipticpartial differential equations under Robbin's boundaryconditions is attempted by means of the Extrapolatedform of the Alternating Direction Implicit methods.A set of varying extrapolation parameters is ...
Lordanidis, KI
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

A NEW APPROACH TO DISINFECTION OF CLEANROOMS (MICROBIOLOGICALLY ASPECTS)

open access: yesРазработка и регистрация лекарственных средств, 2019
Microbiological studies conducted the effectiveness of surfaces decontamination by using potassium iodide submicron aerosol, made by the device Generator of sea air «Aeroiodine». We used bacteria of the genus Staphylococcus as the test cultures.
N. P. Sachivkina
doaj  

Te Aroha o te Hauangiangi : Māori perspectives on healing from substance abuse : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Māori Studies at Te Pūtahi-ā-Toi School of Māori Studies, Massey University, Palmerston North, Aotearoa/New Zealand [PDF]

open access: yes, 2006
This thesis examines and describes Māori cultural components used in the treatment of substance abuse problems in the Taha Māori Programme at Queen Mary Hospital.
Warbrick, Keremete Te Rangimaria
core  

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt   +5 more
wiley   +1 more source

Forschungsperspektiven zu KI, Informationsverhalten und Informationskompetenz

open access: yesBibliothek
Der vorliegende Beitrag berichtet über Konzept und Ergebnisse eines Workshops der Autor*innen auf der internationalen Konferenz für Informationsverhaltensforschung (ISIC 2024).
Michel Antje, Griesbaum Joachim
doaj   +1 more source

La caricature des démocraties africaines avant et après la baule dans le parachutage et en attendant le vote des bêtes sauvages. [PDF]

open access: yesPensées Genre, Penser Autrement, 2022
Cette réflexion porte sur la présence d’éléments de l’histoire politique de l’Afrique francophone dans la fiction romanesque. Par le truchement de la colonisation, l’Afrique occidentale française (AOF) a épousé des valeurs de son ancien maitre ...
Boulkini COULDIATI, Fatimata NOMBRE
doaj  

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