Results 91 to 100 of about 3,228,359 (232)

Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease [PDF]

, 2016
AIMS Arterial spin labelling (ASL) MRI measures perfusion without administration of contrast agent. While ASL has been validated in animals and healthy volunteers (HVs), application to chronic kidney disease (CKD) has been limited. We investigated the
Delles, Christian, Gillis, Keith A., Mark, Patrick B., Mccomb, Christie, Morris, Scott T.W., Patel, Rajan K., Radjenovic, Aleksandra, Roditi, Giles H., Schneider, Markus P., Stevens, Kathryn K.   +9 more
core   +1 more source

Decoding myofibroblast origins in human kidney fibrosis

Nature, 2020
Kidney fibrosis is the hallmark of chronic kidney disease progression; however, at present no antifibrotic therapies exist 1 – 3 . The origin, functional heterogeneity and regulation of scar-forming cells that occur during human kidney fibrosis remain ...
C. Kuppe, Mahmoud M. Ibrahim, J. Kranz, Xiaoting Zhang, S. Ziegler, J. Perales-Patón, J. Jansen, Katharina C. Reimer, James R. Smith, R. Dobie, John R Wilson-Kanamari, Maurice Halder, Yaoxian Xu, Nazanin Kabgani, Nadine Kaesler, Martin Klaus, L. Gernhold, Victor G. Puelles, T. Huber, P. Boor, Sylvia Menzel, R. Hoogenboezem, E. Bindels, J. Steffens, J. Floege, R. Schneider, J. Saez-Rodriguez, N. Henderson, R. Kramann   +28 more
semanticscholar   +1 more source

GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract

Human Genomics
Background Congenital anomalies of the kidney and urinary tract (CAKUT) are prevalent birth defects. Although pathogenic CAKUT genes are known, they are insufficient to reveal the causes for all patients.
Xuanjin Du, Chunyan Wang, Jialu Liu, Minghui Yu, Haixin Ju, Shanshan Xue, Yaxin Li, Jiaojiao Liu, Rufeng Dai, Jing Chen, Yihui Zhai, Jia Rao, Xiang Wang, Yubo Sun, Lei Sun, Xiaohui Wu, Hong Xu, Qian Shen   +17 more
doaj   +1 more source

The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII

Journal of Translational Medicine, 2023
Background Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT.
Liangmei Chen, Xiaofan Li, Yiyao Deng, Jianwen Chen, Mengjie Huang, Fengge Zhu, Zhumei Gao, Lingling Wu, Quan Hong, Zhe Feng, Guangyan Cai, Xuefeng Sun, Xueyuan Bai, Xiangmei Chen   +13 more
doaj   +1 more source

Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]

arXiv, 2023
While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv  

Inter-study reproducibility of arterial spin labelling magnetic resonance imaging for measurement of renal perfusion in healthy volunteers at 3 Tesla [PDF]

, 2014
Background: Measurement of renal perfusion is a crucial part of measuring kidney function. Arterial spin labelling magnetic resonance imaging (ASL MRI) is a non-invasive method of measuring renal perfusion using magnetised blood as endogenous contrast ...
Delles, C., Foster, J.E., Gillis, K.A., Jardine, A.G., Mark, P.B., McComb, C., Morris, S.T.W., Patel, R.K., Roditi, G.H., Schneider, M.P., Taylor, A.H.M.   +10 more
core   +3 more sources

Effect of a Hemodialysis Session on Markers of Inflammation and Endotoxin

International Journal of Inflammation, 2022
Background. People receiving hemodialysis (HD) treatment have higher cardiovascular morbidity and mortality, ascribed to an increased prevalence of traditional cardiovascular risk factors.
Shyam Dheda, David A Vesey, Carmel Hawley, David W Johnson, Magid Fahim   +4 more
doaj   +1 more source

C-arm Tomographic Imaging Technique for Nephrolithiasis and Detection of Kidney Stones [PDF]

arXiv, 2017
In this paper, we investigated a C-arm tomographic technique as a new three dimensional (3D) kidney imaging method for nephrolithiasis and kidney stone detection over view angle less than 180o. Our C-arm tomographic technique provides a series of two dimensional (2D) images with a single scan over 40o view angle.
arxiv  

Identification, Characterization, and Localization of a Novel Kidney Polycystin-1-Polycystin-2 Complex [PDF]

, 2002
The functions of the two proteins defective in autosomal dominant polycystic kidney disease, polycystin-1 and polycystin-2, have not been fully clarified, but it has been hypothesized that they may heterodimerize to form a "polycystin complex" involved ...
Ackermann, Bergsma, Boletta, Cai, Charron, Chen, Foggensteiner, Gallagher, Gonzalez-Perrett, Green, Grupp, Hanaoka, Huan, Hughes, Ibraghimov Beskrovnaya, Ibraghimov Beskrovnaya, Jat, Jat, Lehtonen, Lohning, Lu, Man, Markowitz, Mochizuki, Moy, Nathke, Obermuller, Olmsted, Ong, Ong, Ong, Ong, Pollack, Pritchard, Putney, Qian, Rothman, Scheffers, Tsiokas, Vassilev, Ward, Watnick, Wu, Xu   +43 more
core   +1 more source

Ectopic pelvic kidney associated with uretero-pelvic junction obstruction: a case report

Počki
Ectopic kidneys though uncommon can be associated with other anomalies of the genitourinary system such as uretero-pelvic junction obstruction, vesicoureteral reflux and upper urinary tract abnormalities. These associations present surgical challenges in
U.E. Onwuasoanya, R.K. Agrawal, H.O. Ekwuazi, A. Adetunbi, P. Olorunfemi, O. Ozoh, W. Rex-ogbuku, I. Odunfa   +7 more
doaj   +1 more source