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HYPERTENSION, 2003 Chronic kidney disease1 (CKD) is a worldwide public health problem. In the United States, there is a rising incidence and prevalence of kidney failure, with poor outcomes and high cost.
M. Sarnak +14 more
semanticscholar +1 more source
Blockchain-Powered Supply Chain Management for Kidney Organ Preservation [PDF]
arXiv, 2023 Due to the shortage of available kidney organs for transplants, handling every donor kidney with utmost care is crucial to preserve the organ's health, especially during the organ supply chain where kidneys are prone to deterioration during transportation.
arxiv
Anion transporter: highly cell-type-specific expression of distinct polypeptides and transcripts in erythroid and nonerythroid cells [PDF]
, 1985 Affinity-purified antibodies and cDNA probes specific for the chicken erythrocyte anion transporter (also referred to as band 3) have been used to demonstrate that this protein is expressed in a highly cell- type-specific manner in the avian kidney ...
Cox, John V. +2 more
core +1 more source
Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis [PDF]
, 2015 Extracellular-signal regulated kinase (ERK) activation by MEK plays a key role in many of the cellular processes that underlie progressive kidney fibrosis including cell proliferation, apoptosis and transforming growth factor β1-mediated epithelial to ...
AA Eddy +50 more
core +2 more sources
Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.
New England Journal of Medicine, 2016 BACKGROUND Diabetes confers an increased risk of adverse cardiovascular and renal events. In the EMPA-REG OUTCOME trial, empagliflozin, a sodium-glucose cotransporter 2 inhibitor, reduced the risk of major adverse cardiovascular events in patients with ...
C. Wanner +9 more
semanticscholar +1 more source
BMC Nephrology, 2023 Background Crescentic immunoglobulin A (IgA) nephropathy, defined as > 50% of the glomeruli with crescents, often has a poor renal prognosis. Because of the high prevalence of pre-eclampsia in the second trimester of pregnancy, we often fail to ...
Hisato Shima +8 more
doaj +1 more source
Decision Support System for Renal Transplantation [PDF]
In: Proceedings of the 2018 IISE Annual Conference: 2018; Orlando:
IISE; 2018: 431-436, 2018 The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the paper develops a prediction model that identifies factors that determine the probability of success of renal ...
arxiv +1 more source
Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study. [PDF]
, 2017 Tumor necrosis factor receptor type 1 (TNFR1) is associated with kidney disease and mortality risk in various populations [1], [2]. We evaluated associations of TNFR1 with mortality and mediators of this relationship in doi: 10.1016/j.atherosclerosis ...
Huang, Debbie +4 more
core +2 more sources
Diabetic Kidney Disease: Challenges, Progress, and Possibilities.
American Society of Nephrology. Clinical Journal, 2017 Diabetic kidney disease develops in approximately 40% of patients who are diabetic and is the leading cause of CKD worldwide. Although ESRD may be the most recognizable consequence of diabetic kidney disease, the majority of patients actually die from ...
R. Alicic, M. Rooney, K. Tuttle
semanticscholar +1 more source
Case Reports in Nephrology, 2022 Successful kidney transplantation (KTx) in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) has been reported with excellent patient and graft survival rates.
Reda Laamech +7 more
doaj +1 more source