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Editor's note

Journal of Kidney Cancer and VHL, 2014
Dear fellow researchers,Welcome to the first issue of the Journal of Kidney Cancer and VHL (JKCVHL).JKCVHL is an open access journal created to fill the vacuum for a specialized journal to disseminate information on the advances in kidney cancer and VHL ...
Journal of Kidney Cancer and VHL
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Diabetes and kidney cancer: A direct or indirect association? [PDF]

, 2010
A positive association between diabetes and kidney cancer has been reported in several investigations, but it is unclear whether diabetes or its complications account for this association.
Bahij S. Nuwayhid, Eva L. Evans, Rohit P. Ojha, Tabatha N. Powell, Zuber D. Mulla   +4 more
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PD-L1 detection using 89Zr-atezolizumab immuno-PET in renal cell carcinoma tumorgrafts from a patient with favorable nivolumab response

Journal for ImmunoTherapy of Cancer, 2019
Background Programmed death-ligand 1 (PD-L1) expression in metastatic renal cell carcinoma (RCC) correlates with a worse prognosis, but whether it also predicts responsiveness to anti-PD-1/PD-L1 therapy remains unclear.
Joseph Vento, Aditi Mulgaonkar, Layton Woolford, Kien Nham, Alana Christie, Aditya Bagrodia, Alberto Diaz de Leon, Raquibul Hannan, Isaac Bowman, Renee M. McKay, Payal Kapur, Guiyang Hao, Xiankai Sun, James Brugarolas   +13 more
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Patients With Kidney Cancer [PDF]

, 2012
To develop a preoperative prognostic model in order to predict recurrence-free survival in patients with nonmetastatic kidney cancer.A multi-institutional data base of 1889 patients who underwent surgical resection between 1987 and 2007 for kidney cancer
B. Soyupak, C. Gogus, E. Karabulut, H. Ozen, L. Turkeri, null null, O. Yaycioglu, S. Eskicorapci, S. Yazici, T. Divrik   +9 more
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Acute kidney injury in critically ill cancer patients : an update [PDF]

, 2016
Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer itself or its treatment, these patients ...
Benoit, Dominique, Lameire, Norbert, Van Biesen, Wim, Vanholder, Raymond   +3 more
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Point of care parenchymal volume analyses to estimate split renal function and predict functional outcomes after radical nephrectomy

Scientific Reports, 2023
Accurate prediction of new baseline GFR (NBGFR) after radical nephrectomy (RN) can inform clinical management and patient counseling whenever RN is a strong consideration.
Nityam Rathi, Worapat Attawettayanon, Yosuke Yasuda, Kieran Lewis, Gustavo Roversi, Snehi Shah, Andrew Wood, Carlos Munoz-Lopez, Diego A. Palacios, Jianbo Li, Nour Abdallah, Jared P. Schober, Marshall Strother, Alexander Kutikov, Robert Uzzo, Christopher J. Weight, Mohamed Eltemamy, Venkatesh Krishnamurthi, Robert Abouassaly, Steven C. Campbell   +19 more
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Divergent mutational processes distinguish hypoxic and normoxic tumours. [PDF]

, 2020
Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific ...
Bhandari, Vinayak, Boutros, Paul C, Bristow, Robert G, Li, Constance H, PCAWG Consortium   +4 more
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Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre, Castelletti, Deborah, Fu, Xuebin, Liu, Yang, Mischak, Harald, Mullen, William, Pejchinovski, Martin, Serra, Andreas L., Siwy, Justyna, Wang, Xueqi, Watnick, Terry J.   +10 more
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Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode

Nature Communications, 2020
The human gonadotropin-releasing hormone receptor GnRH1R is a GPCR with an important role in the human reproductive system and of interest as a drug target.
Wei Yan, Lin Cheng, Wei Wang, Chao Wu, Xin Yang, Xiaozhe Du, Liang Ma, Shiqian Qi, Yuquan Wei, Zhiliang Lu, Shengyong Yang, Zhenhua Shao   +11 more
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Progress and Comment on Immunotherapy of Advanced Renal Cell Carcinoma

Zhongliu Fangzhi Yanjiu, 2020
Immunotherapy has made great progress in the treatment of advanced renal cell carcinoma (RCC), since nivolumab was approved for the second-line therapy of advanced RCC.
ZHOU Li, SHENG Xi'nan
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